83280-18-6

Basic information

• Product Name: BOC-phenylalanylprolylglycine benzyl ester
• Synonyms: BOC-phenylalanylprolylglycine benzyl ester
• CAS NO: 83280-18-6
• Molecular Weight: 509.602
• Mol File: 83280-18-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: BOC-phenylalanylprolylglycine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-phenylalanylprolylglycine benzyl ester(83280-18-6)
• EPA Substance Registry System: BOC-phenylalanylprolylglycine benzyl ester(83280-18-6)

Safety Data

• Hazardous Substances Data: 83280-18-6(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 64471-98-3 prolylglycine benzyl ester hydrochloride 
• 7535-56-0 N-t-butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester 
• 1738-68-7 Gly-OBz 
• 31953-80-7 N-tert-butyloxycarbonyl-(2S)-prolyl-glycine benzyl ester 
• 2462-31-9 benzyl 2-aminoacetate hydrochloride 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 3674-06-4 Boc-Phe-ONSu 
• 23420-32-8 N-tert-butoxycarbonyl-L-phenylalanyl-L-proline 
• 1738-76-7 glycine benzyl ester p-toluenesulfonic acid salt 

Downstream Products

• 82289-41-6 des-Tyr¹-β-casomorphin-5 
• 83280-23-3 β-casomorphine monohydrochloride 
• 83280-22-2 Boc-Tyr-Pro-Phe-Pro-Gly-OH 
• 99909-39-4 Boc-Phe-Pro-Gly-Arg(NO₂)-OBzl 
• 115901-40-1 Z-O-benzyltyrosylprolylphenylalanylprolylglycine benzyl ester 
• 103725-70-8 BOC-prolylphenylalanylprolylglycine benzyl ester 
• 72122-63-5 bovine β-casomorphin-5 
• 66211-31-2 N-tert-butyloxycarbonyl-L-phenylalanyl-L-prolylglycine 
• 83280-19-7 phenylalanylprolylglycine benzyl ester hydrochloride 
• 83280-20-0 Z-Pro-Phe-Pro-Gly-OBzl 

Relevant articles and documents

Structure of Halo-toxin Procedured by Phytopathogenic Bacterium, Pseudomonas syringae pv. mori

Halo-toxin was isolated from the incubated medium of Pseudomonas syringae pv. mori which causes halo bright disease against the leaves of mulberry trees.The structure of this compound was revealed to be Pro-Phe-Pro-Gly-Pro-Ile by spectroscopic means and a

Bitter Taste of Synthetic C-Terminal Tetrapeptide of Bovine β-Casein, H-Pro196-Val-Leu-Gly-Pro-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val209-OH, and Its Related Peptides

The primary structure of bovine β-casein contains the partial sequence of -Pro196-Val-Leu-Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val209 in the C-terminal portion.We previously reported that the synthetic C-terminal octapeptide, Arg202-Val209, is extremly bitter with its threshold value 0.004 mM, 250 times as strong as that of caffeine.To further investigate the bitter taste of the C-terminal portion of β-casein, we synthesized the C-terminal tetrapeptide, Pro196-Val209, and some its fragments.A hydrophobic hexapeptide, Pro196-Val201, was twice as bitter as caffein.The bitter taste of decapeptide, Pro200-Val209, was the same as that of Arg202-Val209.Although the tetradecapeptide, Pro196-Val209, was composed of two bitter peptides, Pro196-Val201 and Arg202-Val209, its bitter taste was weaker than that of Arg202-Val209 and its threshold value was 0.015 mM.We suggested that the increase of bitterness in peptides through the introduction of hydrophobic amino acids depended on the number of hydrophobic amino acids added.In addition, the synthetic retro analog of Arg202-Val209 (H-Val-Ile-Ile-Pro-Phe-Pro-Gly-Arg-OH) was not as bitter as Arg202-Val209.This indicated that the sequence of Arg202-Val209 is important for extreme bitterness.

Synthesis and enzymatic degradation of β-casomorphine-5

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