83341-28-0

Basic information

• Product Name: 5-Fluoro-4-Methyl-2-nitrophenol
• Synonyms: 5-Fluoro-4-Methyl-2-nitrophenol
• CAS NO: 83341-28-0
• Molecular Formula: C₇H₆FNO₃
• Molecular Weight: 171.1258432
• Mol File: 83341-28-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Fluoro-4-Methyl-2-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Fluoro-4-Methyl-2-nitrophenol(83341-28-0)
• EPA Substance Registry System: 5-Fluoro-4-Methyl-2-nitrophenol(83341-28-0)

Safety Data

• Hazardous Substances Data: 83341-28-0(Hazardous Substances Data)

Upstream product

• 18349-11-6 1-chloro-5-fluoro-4-methyl-2-nitrobenzene 
• 452-78-8 3-fluoro-4-methyl phenol 

Relevant articles and documents

Novel(1,2,4)triazolo(1,5-a)pyridylphosphine oxide and use thereof

The present invention relates to novel(1,2,4)triazolo(1,5-a)pyridinyl phosphorus oxides and uses thereof. Wherein the compound is a compound represented by a formula I, or a pharmaceutically acceptable salt thereof, or a hydrate thereof, or a solvate thereof, or a metabolite thereof, or a stereoisomer thereof, or a tautomer thereof, or a prodrug thereof, and R1 to R5 are as defined in the specification. The compound disclosed by the invention can be used for preparing a medicine for treating and/or preventing cancers.

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

Tyrosine Kinase Inhibitor And Uses Thereof

Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.

THIAZOLE SULFONAMIDE AND OXAZOLE SULFONAMIDE KINASE INHIBITORS

The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.

2- [ (2-{PHENYLAMINO}-1H-PYRROLO [2, 3-D] PYRIMIDIN-4-YL) AMINO] BENZAMIDE DERIVATIVES AS IGF-1R INHIBITORS FOR THE TREATMENT OF CANCER

Novel pyrrolopyrimidines as shown in formula (I) and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.

Imidazopyridine Kinase Inhibitors

The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.

Palladium-catalyzed C-O bond formation: direct synthesis of phenols and aryl/alkyl ethers from activated aryl halides

A simple and efficient palladium-catalyzed carbon-oxygen bond formation is reported. The palladium-tri-tert-butylphosphine complex was found to be effective in converting haloarenes to corresponding substituted phenols. This methodology offers a direct transformation of aryl halides to phenols, as well as the straightforward application to generate a wide variety of diaryl or alkyl/aryl ethers.

Naphthylenedi(heteroarenes), I. - Synthesis and Spectroscopic Properties of 2,2'-Naphthylenedibenzoxazoles

Starting from 2,2'-(1,4-naphthylene)dibenzoxazole (1a) used as fluorescent whitening agent for polyester fibers and plastics it is systematically investigated how structural modifications affect spectroscopic properties such as absorption, fluorescence, e