84249-14-9

Basic information

• Product Name: 2-Amino-4-bromopyridine
• Synonyms: 2-AMINO-4-BROMOPYRIDINE;4-BROMOPYRIDIN-2-AMINE;4-BROMO-PYRIDIN-2-YLAMINE;AKOS BBS-00001381;AURORA 23224;OTAVA-BB BB7110952492;4-Bromo-2-aminopyridine;4-Bromo-2-amine-pyridin
• CAS NO: 84249-14-9
• Molecular Formula: C₅H₅BrN₂
• Molecular Weight: 173.01
• EINECS: -0
• Product Categories: Heterocyclic Series;pharmacetical;Pyridine series;Amines;Pyridines;Pyridine;Organohalides;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Aromatics;Heterocycles;intermediate
• Mol File: 84249-14-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 136-138°C
• Boiling Point: 268.2 °C at 760 mmHg
• Flash Point: 116 °C
• Appearance: off-white to beige solid
• Density: 1.71 g/cm³
• Storage Temp.: Room temperature.
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 5.72±0.11(Predicted)
• CAS DataBase Reference: 2-Amino-4-bromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-bromopyridine(84249-14-9)
• EPA Substance Registry System: 2-Amino-4-bromopyridine(84249-14-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36-22
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 84249-14-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Beige Solid

InChI:InChI:1S/C5H5BrN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)

Upstream product

• 58530-53-3 2,4-dibromopyridine 
• 5470-66-6 2-methyl-4-nitropyridine N-oxide 

Downstream Products

• 1018814-40-8 7-bromo-2-phenylimidazo[1,2-α]pyridine 
• 808744-34-5 7-bromoimidazo[1,2-a]pyridine 
• 1202704-61-7 1,2-diamino-4-bromopyridin-1-ium-2,4,6-trimethylbenzenesulfonate 
• 1053655-66-5 7-bromo-[1,2,4]triazolo[1,5-a]pyridine 
• 1202701-54-9 (S)-(N-3-(3-fluoro-4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)phenyl)-2-oxo-5-oxazolidinyl)methylacetamide 
• 1202701-61-8 (R)-3-(3-fluoro-4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)phenyl)-5-([1,2,3]triazol-1-yl)methyloxazolidin-2-one 
• 1224740-91-3 4-(2-aminopyridin-4-yl)-3-methylbenzonitrile 
• 1388021-42-8 4-(2-((4-chloro-5-(pyridin-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)methylamino)pyridin-4-yl)-3-methylbenzonitrile 
• 946000-27-7 4-bromo-N,N-dimethylpyridine-2-amine 
• 1184776-68-8 3-(4-bromopyridin-2-yl)-2-(2,6-difluorophenyl)-1,3-thiazolidin-4-one 
• 60781-83-1 4-phenyl-pyridin-2-ylamine 
• 1158787-03-1 N-[(4-bromopyridin-2-yl)carbamoyl]-4-chlorobenzenesulfonamide 
• 1031432-46-8 N-(4-bromopyridin-2-yl)-N′-ethylurea 
• 477726-76-4 4-(2-Amino-pyridin-4-yl)-2-(2-amino-pyrimidin-4-yl)-phenol 

Relevant articles and documents

SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION

The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.