846021-26-9

Basic information

• Product Name: 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID
• Synonyms: 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID;3-Pyridinecarboxylic acid, 2-amino-6-methyl-;2-amino-6-methylpyridine-3-carboxylic acid
• CAS NO: 846021-26-9
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15
• Mol File: 846021-26-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 339.9°C at 760 mmHg
• Flash Point: 159.4°C
• Appearance: /
• Density: 1.337g/cm³
• Vapor Pressure: 3.45E-05mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.11±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID(846021-26-9)
• EPA Substance Registry System: 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID(846021-26-9)

Safety Data

• Hazardous Substances Data: 846021-26-9(Hazardous Substances Data)

Usage

General Description

2-amino-6-methyl-3-pyridinecarboxylic acid is a chemical compound with the molecular formula C8H9N3O2. It is an amino acid derivative and a key building block in the synthesis of organic compounds. 2-AMINO-6-METHYL-3-PYRIDINECARBOXYLIC ACID is commonly used in pharmaceutical and chemical research and is a precursor in the production of various drugs and substances. It is also used in the development and production of pesticides, herbicides, and other agricultural chemicals. Additionally, 2-amino-6-methyl-3-pyridinecarboxylic acid has potential applications in the development of new materials and technologies due to its unique chemical properties.

InChI:InChI=1/C7H8N2O2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H2,8,9)(H,10,11)

Upstream product

• 84647-20-1 2-amino-6-methylpyridine-3-carbonitrile 
• 100524-09-2 2-amino-6-methylnicotinamide 
• 70959-85-2 ethyl 2-amino-6-methylnicotinate 
• 82417-87-6 2-acetylamino-6-methyl-nicotinic acid ethyl ester 
• 4241-27-4 2-hydroxy-6-methylnicotinonitrile 
• 28900-10-9 2-chloro-6-methylnicotinonitrile 
• 30529-70-5 2-chloro-6-methyl nicotinic acid 
• 1359763-35-1 2-(2,2-dimethylpropionylamino)-6-methylnicotinic acid 

Downstream Products

• 98953-24-3 2-acetylamino-6-methyl-nicotinic acid 
• 36075-35-1 7-methyl-1H-pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1185089-98-8 N-[4-(4-methylphenyloxy)phenyl]methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-78-4 N-[4-(4-fluorophenoxy)phenyl]methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-75-1 N-[4-(3-methoxyphenyloxy)phenyl}methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-96-6 N-(3-methoxyphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 849807-77-8 N-(4-benzyloxyphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185090-05-4 N-(4-pentylphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-79-5 N-(2-phenoxythiophen-5-yl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-76-2 N-[3-(4-methoxyphenyloxy)phenyl]methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-91-1 N-(3-phenoxyphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185089-94-4 N-(2-fluoro-3-methoxyphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185090-01-0 N-(3-pentylphenyl)methyl-2-amino-6-methylnicotinic acid amide 
• 1185090-00-9 N-[3-(3-methylphenyloxy)phenyl]methyl-2-amino-6-methylnicotinic acid amide 

Relevant articles and documents

Method for producing 2-amino-6-methylnicotinic acid

The present invention provides a method for producing 2-amino-6-methylnicotinic acid represented by formula [I], wherein the production method comprises: (a) reacting 2-chloro-3-cyano-6-methylpyridine represented by formula [II] in an ammonia aqueous solution to obtain a reaction solution containing 2-amino-6-methylnicotinamide represented by formula [III]; and (b) removing the ammonia from the reaction solution, then reacting the 2-amino-6-methylnicotinamide represented by formula [III] with a base to produce 2-amino-6-methylnicotinic acid represented by formula [I].

COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS

Disclosed is a composition for agricultural use, which is used for controlling or preventing plant diseases caused by plant pathogens. The composition for agricultural use contains a compound represented by formula (1), a salt thereof or a hydrate of the compound or the salt. (1) [In the formula, Z represents an oxygen atom, a sulfur atom or NRz; and E represents a furyl group, a thienyl group, a pyrrolyl group, a tetrazolyl group, a thiazolyl group, a pyrazolyl group, a phenyl group or the like.]

AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.