84758-81-6

Basic information

• Product Name: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride
• Synonyms: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride;2-Amino-2-methylpropionic acid tert-butyl ester hydrochloride;tert-Butyl 2-amino-2-methylpropanoate hydrochloride;EOS-62338
• CAS NO: 84758-81-6
• Molecular Formula: C₈H₁₇NO₂*ClH
• Molecular Weight: 195.68702
• Mol File: 84758-81-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Soluble in water or 1% acetic acid.
• CAS DataBase Reference: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(84758-81-6)
• EPA Substance Registry System: Alanine, 2-Methyl-, 1,1-diMethylethyl ester, hydrochloride(84758-81-6)

Safety Data

• Hazardous Substances Data: 84758-81-6(Hazardous Substances Data)

Usage

Uses

tert-Butyl 2-aminoisobutyrate hydrochloride is used as intermediates.

Upstream product

• 4512-31-6 benzyloxycarbonyl-α-aminoisobutyric acid tert-butyl ester 

Downstream Products

• 847165-35-9 tert-butyl N-[N-benzyloxycarbonyl-(S)-phenylalanyl]-2,2-dimethylglycinate 
• 848155-46-4 H-Leu-Aib-Phe-Aib-OtBu 
• 848155-42-0 tert-butyl N-{N-[N-(N-benzyloxycarbonyl-(S)-leucyl)-2,2-dimethylglycyl]-(S)-phenylalanyl}-2,2-dimethylglycinate 
• 848155-47-5 H-Gly-Aib-Leu-Aib-Phe-Aib-OtBu 
• 848155-43-1 tert-butyl N-[N-(N-{N-[N-(N-benzyloxycarbonyl-glycyl)-2,2-dimethylglycyl]-(S)-leucyl}-2,2-dimethylglycyl)-(S)-phenylalanyl]-2,2-dimethylglycinate 
• 847165-58-6 H-Phe-Aib-O^tBu 
• 1090903-31-3 2-methyl-2-(2-nitro-phenylamino)-propionic acid tert-butyl ester 
• 1155803-04-5 C₃₆H₃₈FN₃O₆ 
• 143782-20-1 4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile 
• 1006899-17-7 tert-butyl 2-methyl-2-[3-(4-methylsulfanyl-3-trifluoromethylphenyl)ureido]propionate 
• 1192477-69-2 C₁₅H₂₉NO₂ 
• 1192465-30-7 Z-CF₃-Ala-Aib-OtBu 
• 1179906-97-8 tert-butyl 2-methyl-2-(2-phenoxybenzylamino)propionate 
• 1179804-51-3 tert-butyl 2-(2-benzylbenzylamino)-2-methylpropionate 

Relevant articles and documents

SYNTHESE VON 2-METHYLALANIN-PEPTIDEN, DIE pH-ABHAENGIGKEIT IHRER 13C-NMR-SPECTREN UND EINE NEUE METHODE ZUR AUSWERTUNG UEBER CS-DIAGRAMME

The uncommon amino-acid 2-methylalanine (α-aminoisobutiryc acid, Aib) was investigated by 13C-NMR.The chemical shifts of amino- or carboxy-protected derivates of Aib and of protected oligopeptides are discussed with respect to neighbouring groups and amino acids.The pH-dependence of the 13C-NMR spectra of Aib, Aib-Ala, Ala-Aib, Aib-Ala-Aib and Aib-Ala-Aib-Ala-Aib was studied.Using these examples, a new and advantageous method is demonstrated for the first time for the evaluation of NMR titration curves, which uses so-called chemical shift diagrams (CS diagrams).