853109-56-5

Basic information

• Product Name: 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid
• Synonyms: 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid
• CAS NO: 853109-56-5
• Molecular Weight: 345.555
• Mol File: 853109-56-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid(853109-56-5)
• EPA Substance Registry System: 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid(853109-56-5)

Safety Data

• Hazardous Substances Data: 853109-56-5(Hazardous Substances Data)

Upstream product

• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 367-24-8 4-bromo-2-fluoroaniline 

Downstream Products

• 853109-58-7 2-(4-bromo-2-fluorophenylamino)-6-chloro-nicotinic acid methyl ester 

Relevant articles and documents

Heterocyclic inhibitors of MEK and methods of use thereof

Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.