853784-41-5

Basic information

• Product Name: 3-(trifluoroMethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3- b]pyridine
• Synonyms: 3-(trifluoroMethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3- b]pyridine;3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine
• CAS NO: 853784-41-5
• Molecular Formula: C₇H₈F₃N₃
• Molecular Weight: 191.1537296
• Mol File: 853784-41-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(trifluoroMethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3- b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(trifluoroMethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3- b]pyridine(853784-41-5)
• EPA Substance Registry System: 3-(trifluoroMethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3- b]pyridine(853784-41-5)

Safety Data

• Hazardous Substances Data: 853784-41-5(Hazardous Substances Data)

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Relevant articles and documents

Dipeptidyl peptidase IV inhibitors derived from β-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole

A series of β-aminoacylpiperidines bearing various fused five-membered heterocyclic rings was synthesized as dipeptidyl peptidase IV inhibitors. Potent and relatively selective inhibition could be obtained, depending on choice of heterocycle, regioisomerism, and substitution. In particular, one analog (74, DPP-IV IC50 = 26 nM) exhibited good oral bioavailability and acceptable half-life in the rat, albeit with rather high clearance.