85828-28-0

Basic information

• Product Name: L-N^α-(Phenylsulfonyl)-N^ε-(ethoxycarbonyl)lysine
• CAS NO: 85828-28-0
• Molecular Weight: 358.415
• Mol File: 85828-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-N^α-(Phenylsulfonyl)-N^ε-(ethoxycarbonyl)lysine(CAS DataBase Reference)
• NIST Chemistry Reference: L-N^α-(Phenylsulfonyl)-N^ε-(ethoxycarbonyl)lysine(85828-28-0)
• EPA Substance Registry System: L-N^α-(Phenylsulfonyl)-N^ε-(ethoxycarbonyl)lysine(85828-28-0)

Safety Data

• Hazardous Substances Data: 85828-28-0(Hazardous Substances Data)

Upstream product

• 5701-16-6 L-N^ε-(Ethoxycarbonyl)lysine 
• 98-09-9 benzenesulfonyl chloride 
• 657-27-2 L-Lysine hydrochloride 

Downstream Products

• 85828-37-1 (S)-5-<(Phenylsulfonyl)amino>-9-<(ethoxycarbonyl)-amino>-4-nonenone 

Relevant articles and documents

α-Amino Acids as Chiral Educts for Asymmetric Products. Aminoacylation of Metallo Alkyls and Alkenyls

α-Amino acids have been developed as educts for the preparation of optically pure α-amino aliphatic ketones.The amino group of the L-amino acid was first blocked as a suitable acyl derivative, namely, acetyl, benzoyl, ethoxycarbonyl, or benzenesulfonyl.Then the lithium carboxylate was formed and treated with alkyl- and alkenyllithium or Grignard reagents.Thus butyl, allyl, and vinyl organometallics were added to the lithium carboxylates of L-α-N-substituted alanine, valine, O-benzyltyrosine, methionine, serine, and ε-(ethoxycarbonyl)lysine to yield the corresponding optically pure ketones, protected as amides, sulfonamides, or carbamates.