85989-65-7

Basic information

• Product Name: C₈H₈ClNO₃
• Synonyms: C₈H₈ClNO₃
• CAS NO: 85989-65-7
• Molecular Weight: 201.609
• Mol File: 85989-65-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈H₈ClNO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₈ClNO₃(85989-65-7)
• EPA Substance Registry System: C₈H₈ClNO₃(85989-65-7)

Safety Data

• Hazardous Substances Data: 85989-65-7(Hazardous Substances Data)

Upstream product

• 67-62-9 O-Methylhydroxylamin 
• 7693-45-0 4-Chlorophenyl chloroformate 

Downstream Products

• 33026-74-3 1-Methoxy-3-phenyl-harnstoff 
• 106-48-9 4-chloro-phenol 

Relevant articles and documents

KINETICS AND MECHANISM OF HYDROLYSIS OF ARYL N-METHOXYCARBAMATES AND THEIR DERIVATIVES

Hydrolysis kinetics have been studied of 3- and 4-substituted phenyl N-methoxycarbamates and their N-methyl derivatives in aqueous buffers at 60 deg C.The N-methyl derivatives show linear dependence of the rate constants on concentration of hydroxyl ion in the pH range measured.Hydrolysis of aryl N-methoxycarbamates is independent of hydroxyl ion concentration at higher pH values.Logarithms of the rate constants have been correlated with the substituent constants ?.The calculated values 0.9 for N-methyl derivatives, 4.5 and 3.3 for aryl N-methoxy-carbamates in theregions of linear pH-dependency and pH-independency, respectively, suggest that the hydrolysis follows the BAc2 and ElcB mechanisms in the case of the N-methyl derivatives and aryl N-methoxycarbamates, respectively.Difference between the two ρ constants for the hydrolysis of aryl N-methoxycarbamates agrees with the found value ρ=1.2 for dissociation constants of these compounds.The elimination mechanism has been confirmed by reaction of the isocyanate formed with added aniline to give the respective urea.