Welcome to LookChem.com Sign In|Join Free

CAS

  • or

861218-15-7

Post Buying Request

861218-15-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

861218-15-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 861218-15-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,2,1 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 861218-15:
(8*8)+(7*6)+(6*1)+(5*2)+(4*1)+(3*8)+(2*1)+(1*5)=157
157 % 10 = 7
So 861218-15-7 is a valid CAS Registry Number.

861218-15-7Downstream Products

861218-15-7Relevant articles and documents

Benzothiophene derivatives and medical use thereof for treating or preventing retinal diseases

-

Paragraph 0059-0062, (2021/03/30)

The present invention relates to a novel benzo[b]thiophene derivative having RIPK1 inhibitory activity, a method for preparing the same, and a pharmaceutical composition for preventing or treating a retinal disease containing the same as an active component. According to the present invention, the novel benzo[b]thiophene derivative, or a pharmaceutically acceptable salt thereof has an excellent effect of inhibiting receptor-interacting serine/threonine-protein kinase 1 (RIPK1), thereby being usefully used for treating or preventing various retinal diseases including macular degeneration.

4-Substituted (benzo[b]thiophene-2-carbonyl)guanidines as novel Na +/H+ exchanger isoform-1 (NHE-1) inhibitors

Lee, Sunkyung,Lee, Hyunsuk,Kyu, Yang Yi,Byung, Ho Lee,Yoo, Sung-Eun,Lee, Kyunghee,Nam, Sook Cho

, p. 2998 - 3001 (2007/10/03)

A series of 4-substituted (benzo[b]thiophene-2-carbonyl)guanidines was synthesized and evaluated for the NHE-1 inhibitory activity and cardioprotective efficacy both in vitro and in vivo. Several analogs exhibited a strong inhibition on NHE-1, and which was generally well correlated with their cardioprotective efficacy. Especially the 4-nitro 20 and cyano 50 compounds excellently improved the cardiac function and reduced infarct size against ischemia/reperfusion injury.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 861218-15-7