86148-27-8

Basic information

• Product Name: 1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene
• CAS NO: 86148-27-8
• Molecular Formula: C₁₆H₁₄S₂
• Molecular Weight: 270.419
• Mol File: 86148-27-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 418.6°Cat760mmHg
• Flash Point: 211.2°C
• Density: 1.19g/cm³
• CAS DataBase Reference: 1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene(86148-27-8)
• EPA Substance Registry System: 1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene(86148-27-8)

Safety Data

• Hazardous Substances Data: 86148-27-8(Hazardous Substances Data)

Usage

General Description

1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene, also known as MPTSESB, is a chemical compound with a complex molecular structure. It consists of a benzene ring with a methyl group at the 1st position, a sulfanyl group at the 4th position, and an ethynylsulfanyl group attached to the 2nd position of the benzene ring. Additionally, there is a 4-methylphenyl sulfanyl group bonded to the ethynylsulfanyl group. 1-methyl-4-[2-(4-methylphenyl)sulfanylethynylsulfanyl]benzene has potential applications in organic chemistry and materials science due to its unique structure and reactivity. Additionally, it may have biological activity and could be of interest in pharmaceutical research. Due to the complexity of its structure, MPTSESB requires careful handling and proper safety measures when used in laboratory and industrial settings.

Upstream product

• 7572-29-4 dichloroethyne 
• 106-45-6 para-thiocresol 
• 5324-85-6 1,2-bis-p-tolylsulfanyl-ethene 
• 39549-10-5 1-[(4-methylphenyl)sulfanyl]pyrrolidine-2,5-dione 
• 65032-27-1 ethynylmagnesium chloride 
• 40976-96-3 tolyl 2,2-dichlorovinyl sulfide 
• 32294-60-3 diphenyl ditelluride 
• 4526-50-5 (E)-1,2-dichloro-1,2-bis-p-tolylsulfanyl-ethene 
• 430-58-0 1,2-dichloro-2-fluoroethene 
• 540-49-8 cis+trans-dibromoethylene 

Downstream Products

• 103-19-5 di(p-tolyl) disulfide 
• 3996-29-0 2-[(4-methylphenyl)thio]acetic acid 
• 39837-43-9 1,2-bis-(toluene-4-sulfonyl)-1-p-tolylsulfanyl-ethane 
• 39837-39-3 1,1,2-tris-(toluene-4-sulfonyl)-ethane 
• 34726-90-4 trans-1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethene 
• 32018-25-0 1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethane 
• 3937-96-0 tosylacetic acid 
• 5324-85-6 1,2-bis-p-tolylsulfanyl-ethene 
• 95432-39-6 p-tolylsulfanyl-acetaldehyde di-p-tolyldithioacetal 
• 21213-28-5 1,2-bis-(toluene-4-sulfonyl)-ethene 
• 100557-90-2 (toluene-4-sulfonyl)-acetaldehyde phenylhydrazone 
• 144488-85-7 1-(toluene-4-sulfinyl)-2-(toluene-4-sulfonyl)-ethene 
• 109410-45-9 toluene-4-sulfinic acid ; compound with phenylhydrazine 
• 4526-52-7 (Z)-1,2-dichloro-1,2-bis-(toluene-4-sulfonyl)-ethene 

Relevant articles and documents

Substituted alkyne synthesis under nonbasic conditions: copper carboxylate-mediated, palladium-catalyzed thioalkyne-boronic acid cross-coupling.

[figure: see text] A new methodology for the synthesis of substituted alkynes is described. In the presence of copper(I) thiophene-2-carboxylate (CuTC) or copper (I) 3-methylsalicylate (CuMeSal), the palladium-catalyzed cross-coupling of thioalkyne derivatives with boronic acids affords functionalized alkynes in yields ranging from 39 to 91%. This coupling occurs efficiently under mild, nonbasic conditions with a wide variety of thioalkynes and boronic acids, providing a reaction complementary to the Sonogashira protocol.

A New Approach to the Synthesis of Symmetrical Bis(organylchalcogeno)acetylenes: Scope and Limitations

A new general method to prepare bis(organylchalcogeno)acetylenes R-Y-CC-Y-R (Y = S, Se, Te) by dehydrochlorination of the corresponding 1,2-bis(organylchalcogeno)chloroethylenes R-Y-CH=CCl-Y-R with tert-BuOK/tert-BuOH and/or KOH/DMSO is developed.Dechlorination of 1,2-bis(organylchalcogeno)-1,2-dichloroethylenes R-Y-CCl=CCl-Y-R (Y = S, Se, Te) with BuLi in ether or THF is effective only for sulfur derivatives.With Y = Se and alkyl substituents, substitution of the chlorine atom by a butyl group takes place giving rise to 5,6-bis(alkylseleno)dec-5-ene .With aryl substituents, an attack of the ArSe-group by the Bu-radical is observed leading to an aryl butyl selenide.In the case of the tellurium compound Ph-Te-CCl=CCl-Te-Ph, there is a competition between dechlorination to give Ph-Te-CC-Te-Ph, and substitution to produce the phenyl butyl telluride. - Keywords: bis(organylchalcogeno)acetylene; 1,2-bis(organylchalcogeno)chloroethylene; 1,2-bis(organochalcogeno)-1,2-dichloroethylene.

A broad scope highly efficient synthesis of bis(R-thio)acetylenes

Treatment of dichloroacetylene with two equivalents of a thiol and two equivalents of potassium hydride in THF solution affords the corresponding bis(R-thio)acetylene in high yield.