863-03-6

Basic information

• Product Name: EPICATECHIN
• Synonyms: Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, cis-;Ccris 9285;Epicatechin-3-galloyl ester;[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl]3,4,5-trihydroxybenzoate
• CAS NO: 863-03-6
• Molecular Formula: C₂₂H₁₈O₁₀
• Molecular Weight: 442.38
• Mol File: 863-03-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 861.7°C at 760 mmHg
• Flash Point: 305°C
• Appearance: /
• Density: 1.8g/cm³
• Vapor Pressure: 3.33E-31mmHg at 25°C
• Refractive Index: 1.825
• PKA: 7.75±0.25(Predicted)
• CAS DataBase Reference: EPICATECHIN(CAS DataBase Reference)
• NIST Chemistry Reference: EPICATECHIN(863-03-6)
• EPA Substance Registry System: EPICATECHIN(863-03-6)

Safety Data

• Hazardous Substances Data: 863-03-6(Hazardous Substances Data)

Usage

Definition

ChEBI: A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3S)-hydroxy group of (+)-epicatechin.

InChI:InChI=1/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m0/s1

Upstream product

• 1255211-38-1 platanoside-A 
• 108-98-5 thiophenol 
• 1255211-63-2 platanoside-B 
• 1309248-10-9 (-)-5,7-O-dipropionyl-3',4'-O-dipropionyl-3'',4'',5''-O-tripropionylepicatechin-3-O-gallate 
• 1309248-11-0 (-)-5,7-O-dibutyryl-3',4'-O-dibutyryl-3'',4'',5''-O-tributyrylepicatechin-3-O-gallate 
• 1309248-12-1 (-)-5,7-O-diisobutyryl-3',4'-O-diisobutyryl-3'',4'',5''-O-triisobutyrylepicatechin-3-O-gallate 
• 1309248-14-3 (-)-5,7-O-divaleroyl-3',4'-O-divaleroyl-3'',4'',5''-O-trivaleroylepicatechin-3-O-gallate 
• 20728-98-7 (-)-5,7-O-diacetyl-3',4'-O-diacetyl-3'',4'',5''-triacetylepicatechin-3-O-gallate 
• 154-23-4 catechin 
• 918158-03-9 (1S,2S)-3-[2,4-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-(3,4-bis-benzyloxy-phenyl)-propane-1,2-diol 
• 918157-97-8 (E)-3-[2,4-bis(benzyloxy)-6-(tert-butyldimethylsilyloxy)phenyl]-1-[3,4-bis(benzyloxy)phenyl]propene 
• 732298-11-2 (+)-(1S,2S)-3-[2,4-bis(benzyloxy)-6-hydroxyphenyl]-1-[3,4-bis(benzyloxy)phenyl]propane-1,2-diol 
• 732298-08-7 (E)-3-[2,4-bis(benzyloxy)-6-hydroxyphenyl]-1-[3,4-bis(benzyloxy)phenyl]propene 
• 20728-73-8 5,7,3',4'-tetra-O-benzyl-(+)-catechin 

Downstream Products

• 621-54-5 3-(3-hydroxyphenyl)-propanoic acid 
• 31129-95-0 5-(3′-hydroxyphenyl)valeric acid 
• 6500-64-7 5-(3'-methoxyphenyl)pentanoic acid 
• 31129-94-9 5-(3′,4′,5′-trihydroxyphenyl)valeric acid 
• 111397-00-3 (2S)-1-(3',4'-dihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl)propan-2-ol 
• 191666-22-5 (4R)-5-(3,4-dihydroxyphenyl)-γ-valerolactone 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 89064-33-5 procyanidin B₄ 3'-O-gallate 
• 79907-44-1 procyanidin B₂-3,3'-di-O-gallate 
• 28543-07-9 theaflavin-3-gallate 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 1256244-33-3 theaflavanin 3-O-gallate 
• 1256244-36-6 (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 2,3,4,6-tetrahydroxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 

Relevant articles and documents

Study on in Vitro Preparation and Taste Properties of N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols

N-ethyl-2-pyrrolidinone-substituted flavan-3-ols (EPSFs) were prepared by an in vitro model reaction, and the taste thresholds of EPSFs and their dose-over-threshold factors in large-leaf yellow tea (LYT) were investigated. The effects of initial reactant

METHODS OF TREATING COGNITIVE AND BEHAVIORAL IMPAIRMENT IN DOWN SYNDROME AND ALZHEIMERS DISEASE PATIENTS

The present invention relates to methods of treating cognitive and behavioral impairment in Down syndrome and/or Alzheimer's disease patients, Alzheimer's disease, neurodegenerative disease, cancer, DYRK1A-mediated disorders and methods of modulating and inhibiting DYRK1-A comprising use of catechins.

New oligomeric proanthocyanidin glycosides platanoside-A and platanoside-B from Platanus orientalis trunk bark

Two new oligomeric proanthocyanidin glycosides were isolated from trunk bark of Platanus orientalis. Their structures and relative configurations were found to be 7-O-β-D-Glcp-(-)-epicatechin-(4β-8)-(-)- epicatechin(4β-8)-(-)-epicatechin-3-O-gallate (plat