863988-32-3

Basic information

• Product Name: 2-(4-methylpyridin-2-yl)phenol
• Synonyms: 2-(4-methylpyridin-2-yl)phenol
• CAS NO: 863988-32-3
• Molecular Weight: 185.225
• Mol File: 863988-32-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(4-methylpyridin-2-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylpyridin-2-yl)phenol(863988-32-3)
• EPA Substance Registry System: 2-(4-methylpyridin-2-yl)phenol(863988-32-3)

Safety Data

• Hazardous Substances Data: 863988-32-3(Hazardous Substances Data)

Upstream product

• 100004-77-1 2-(2-methoxyphenyl)-4-methylpyridine 
• 3475-21-6 4-methyl-2-phenylpyridine 
• 98-80-6 phenylboronic acid 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 4926-28-7 2-Bromo-4-picoline 
• 1003-67-4 4-methylpyridine-1-oxide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 5720-06-9 2-Methoxyphenylboronic acid 

Relevant articles and documents

Visible Light Induced Rhodium(I)-Catalyzed C?H Borylation

An efficient visible light induced rhodium(I)-catalyzed regioselective borylation of aromatic C?H bonds is reported. The photocatalytic system is based on a single NHC?RhI complex capable of both harvesting visible light and enabling the bond breaking/forming at room temperature. The chelating nature of the NHC-carboxylate ligand was critical to ensure the stability of the RhI complex and to provide excellent photocatalytic activities. Experimental mechanistic studies evidenced a photooxidative ortho C?H bond addition upon irradiation with blue LEDs, leading to a cyclometalated RhIII-hydride intermediate.

Aerobic Direct C(sp2)-H Hydroxylation of 2-Arylpyridines by Palladium Catalysis Induced with Aldehyde Auto-Oxidation

Herein we present a Pd-catalyzed direct C-H hydroxylation of 2-arylpyridines using molecular oxygen (O2) as the sole oxidant. The key aspects of the method include: (a) the activation of molecular oxygen with a nontoxic and inexpensive aldehyde

Direct ortho-Hydroxylation of 2-Phenylpyridines using Palladium(II) Chloride and Hydrogen Peroxide

Direct functionalization of the ubiquitous C-H bond is receiving much attention because complex structures can be formed from simple precursors. This paper reports a useful method for the direct hydroxylation of 2-phenylpyridines using palladium(II) chloride and aqueous hydrogen peroxide. In this method, hydrogen peroxide, which has high atom efficiency, is employed as the oxidant and phenol derivatives are generated via C-H activation.