86517-38-6

Basic information

• Product Name: bromo-2 trimethylsilyloxy-1 morpholino-3 phenyl-3 propene-1
• CAS NO: 86517-38-6
• Molecular Weight: 370.362
• Mol File: 86517-38-6.mol

Chemical Properties

• CAS DataBase Reference: bromo-2 trimethylsilyloxy-1 morpholino-3 phenyl-3 propene-1(CAS DataBase Reference)
• NIST Chemistry Reference: bromo-2 trimethylsilyloxy-1 morpholino-3 phenyl-3 propene-1(86517-38-6)
• EPA Substance Registry System: bromo-2 trimethylsilyloxy-1 morpholino-3 phenyl-3 propene-1(86517-38-6)

Safety Data

• Hazardous Substances Data: 86517-38-6(Hazardous Substances Data)

Upstream product

• 13368-42-8 4-(trimethylsilyl)morpholine 
• 5443-49-2 α-bromocinnamaldehyde 
• 33603-90-6 (2Z)-2-bromo-3-phenyl-2-propenal 

Relevant articles and documents

Nucleophilic Addition of Trimethylsilylamines to 2-Halo-2-alkenals

2-Halo-2-alkenals react with trimethylsilyl derivatives of secondary amines to give the products of 1,2- and 1,4-addition. Both the structure of the starting aldehyde and the nature of the substituent at the nitrogen atom are responsible for reaction selectivity.

Reaction des amines secondaires avec les aldehydes α,β-dibromes. Preparation d'α,β-diaminoaldehydes derives du cinnamaldehyde et nouvelle voie d'acces aux diamino-1,2 ethylenes

Secondary amines react with α-bromocinnamaldehyde to yield various 2,3-bisdialkylamino-3-phenylpropanals.These diaminoaldehydes undergo two competitive rections respectively leading to α-aminocinnamaldehyde and 1,2-diamino-ethylene.Experimental conditions selectively yielding one of these compound have been studied.With 2,3-dibromobutanal the same reaction does not afford diaminoaldehyde but 1,2-diaminoethylene and a new compound, 1,2,3-triamino-1-butene.A possible reaction mechanism is discussed and a new, general one-pot synthesis of 1,2-diaminoethylene from 2-butenal with good yields is described.