865980-96-7

Basic information

• Product Name: (1R,2R)-N¹-cyclohexyl-1,2-diphenylethane-1,2-diamine
• Synonyms: (1R,2R)-N¹-cyclohexyl-1,2-diphenylethane-1,2-diamine
• CAS NO: 865980-96-7
• Molecular Weight: 294.44
• Mol File: 865980-96-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1R,2R)-N¹-cyclohexyl-1,2-diphenylethane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-N¹-cyclohexyl-1,2-diphenylethane-1,2-diamine(865980-96-7)
• EPA Substance Registry System: (1R,2R)-N¹-cyclohexyl-1,2-diphenylethane-1,2-diamine(865980-96-7)

Safety Data

• Hazardous Substances Data: 865980-96-7(Hazardous Substances Data)

Upstream product

• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 108-94-1 cyclohexanone 

Downstream Products

• 1445582-60-4 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-(cyclohexylamino)-1,2-diphenylethyl)thiourea 

Relevant articles and documents

Organocatalytic asymmetric aldol reaction using protonated chiral 1,2-diamines

Organic-catalyzed stereoselective reactions have gained attention because they avoid the problems associated with metal catalysts, but existing catalysts based on proline have limitations. Therefore, (R,R)-(+)-1,2-diphenylethylenediamine (DPEN) was select

Expanding the Family of Hoveyda-Grubbs Catalysts Containing Unsymmetrical NHC Ligands

A series of Hoveyda-Grubbs second-generation catalysts containing N-alkyl/N′-aryl N-heterocyclic carbene (NHC) ligands were synthesized and investigated in representative olefin metathesis reactions. Steric perturbations of unsymmetrical NHCs were achieved through modulation of the hindrance of alkyl (neopentyl, neophyl, cyclohexyl) and aryl (2-isopropylphenyl, mesityl) substituents at the nitrogen atoms in combination with different backbone configurations (syn and anti). The NHC substitution patterns strongly influence the stability and reactivity of the corresponding complexes. In general, complexes bearing an anti NHC backbone are more stable and more active than their corresponding syn isomers. In both the series, the presence of bulky, highly branched N-alkyl groups tends to give reduced catalytic differences between syn and anti isomers, whereas the nature of the N′-aryl substituent (2-isopropylphenyl or mesityl) gives rise to different activity and/or selectivity. Of note, an N′-mesityl catalyst with anti backbone was found to be highly competent in the ethenolysis of ethyl oleate, achieving up to 90% selectivity for the formation of terminal olefins.

Novel olefin metathesis ruthenium catalysts bearing backbone-substituted unsymmetrical NHC ligands

Stable Ru-based catalysts containing unsymmetrical N-heterocyclic carbene (NHC) ligands with phenyl substituents on the backbone in syn and anti stereochemical relationships have been easily prepared and fully characterized. Preliminary investigation reve