86718-07-2

Basic information

• Product Name: 4-(IMIDAZOL-1-YL)-BENZOIC ACID ETHYL ESTER
• Synonyms: 4-(IMIDAZOL-1-YL)-BENZOIC ACID ETHYL ESTER;RARECHEM AL BI 0793;Ethyl 4-Imidazolylbenzoate;Ethyl 4-(1H-Imidazol-1-yl)benzoate;Ethyl 4-(1-IMidazolyl)benzoate
• CAS NO: 86718-07-2
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.24
• Product Categories: Acids and Derivatives;Heterocycles
• Mol File: 86718-07-2.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 366 °C at 760 mmHg
• Flash Point: 175.2 °C
• Appearance: /
• Density: 1.15 g/cm³
• Vapor Pressure: 1.51E-05mmHg at 25°C
• Refractive Index: 1.574
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(IMIDAZOL-1-YL)-BENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(IMIDAZOL-1-YL)-BENZOIC ACID ETHYL ESTER(86718-07-2)
• EPA Substance Registry System: 4-(IMIDAZOL-1-YL)-BENZOIC ACID ETHYL ESTER(86718-07-2)

Safety Data

• Hazardous Substances Data: 86718-07-2(Hazardous Substances Data)

Usage

Uses

Ethyl 4-(1H-imidazol-1-yl)benzoate

InChI:InChI=1/C12H12N2O2/c1-2-16-12(15)10-3-5-11(6-4-10)14-8-7-13-9-14/h3-9H,2H2,1H3

Upstream product

• 288-32-4 1H-imidazole 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 4334-88-7 p-ethoxycarbonylphenylboronic acid 
• 1149-38-8 4-ethoxycarbonylphenyl N,N-dimethylsulfamate 
• 502140-40-1 C₁₄H₁₉NO₄ 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 50-00-0 formaldehyd 
• 127-19-5 N,N-dimethyl acetamide 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 131543-46-9 Glyoxal 
• 94-09-7 p-aminoethylbenzoate 
• 10040-98-9 1-(4-formylphenyl)-1H-imidazole 

Downstream Products

• 17616-04-5 4-(1H-imidazol-1-yl)benzoic acid 
• 1176198-66-5 1-(4-(ethoxycarbonyl)phenyl)-3-hexyl-1H-imidazolium bromide 
• 1286795-93-4 1-(4-(ethoxycarbonyl)phenyl)-3-hexyl-1H-imidazolium bis(trifluoromethanesulfonyl)amide 
• 1176198-65-4 1-(4-(ethoxycarbonyl)phenyl)-3-propyl-1H-imidazolium bromide 
• 1266193-16-1 4-(1H-imidazol-1-yl)phenylmethyl bromide hydrobromide 
• 139277-63-7 3-(4-Imidazol-1-yl-phenyl)-propionic acid hydrazide 
• 143426-74-8 3-(4-Imidazol-1-yl-phenyl)-propionic acid ethyl ester 
• 143426-66-8 ethyl 4-(1-imidazolyl)phenylacetate 
• 139277-59-1 (4-Imidazol-1-yl-phenyl)-acetic acid hydrazide 
• 74002-94-1 (E)-3-(4-Imidazol-1-yl-phenyl)-acrylic acid ethyl ester 
• 1000543-86-1 (4-Imidazol-1-yl-phenyl)-acetic acid 
• 143426-57-7 (4-Imidazol-1-yl-phenyl)-acetonitrile 
• 10040-98-9 1-(4-formylphenyl)-1H-imidazole 

Relevant articles and documents

N -Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe3O4@SiO2 modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental analysis techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N-arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity. This journal is

An in situ generated CuI/metformin complex as a novel and efficient catalyst for C-N and C-O cross-coupling reactions

An in situ generated complex of copper(I) and a biguanide, namely metformin, was found to be a highly efficient homogeneous catalyst in N/O-arylation reactions. The O-arylation of substituted phenols with various aryl iodides and bromides was also achieved using this copper catalyst to afford diaryl ethers in good to excellent yields in DMF. This heterogeneous copper catalyst also promotes the N-arylation of imidazole with a variety of aryl halides (Cl, Br, I) in acetonitrile.

Highly efficient ci￡n bond forming reactions in water catalyzed by copper(i) iodide with calix[4]arene supported amino acid ionic liquid

A novel and effective protocol has been developed for the Ullmann-type Ci￡N coupling reaction catalyzed by calix[4]arene supported amino acid ionic liquid and copper(I) iodide in water under microwave irradiation condition. The protocol uses calix[4]arene supported amino acid ionic liquid as double function of the ligand and phase-transfer catalyst, and shows good tolerance in good to excellent yields. A novel and effective protocol has been developed for the Ullmann-type Ci￡N coupling reaction catalyzed by calix[4]arene supported amino acid ionic liquid and copper(I) iodide in water under microwave irradiation condition. The protocol uses calix[4]arene supported amino acid ionic liquid as double function of the ligand and phase-transfer catalyst, and shows good tolerance in good to excellent yields. Copyright