871241-98-4

Basic information

• Product Name: (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-ol
• Synonyms: (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-ol
• CAS NO: 871241-98-4
• Molecular Weight: 438.564
• Mol File: 871241-98-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-ol(871241-98-4)
• EPA Substance Registry System: (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-ol(871241-98-4)

Safety Data

• Hazardous Substances Data: 871241-98-4(Hazardous Substances Data)

Upstream product

• 871241-97-3 (E)-1,3-bis(4-[tetrahydro-2H-pyran-2-yloxy]phenyl)pent-4-en-1-one 

Downstream Products

• 17676-24-3 (-)-trans-Hinokiresinol 
• 185020-38-6 (+)-(7R,E)-hinokiresinol 
• 175520-27-1 (E)-4,4'-(3-ethenyl-1-propene-1,3-diyl)bisphenol 

Relevant articles and documents

Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy

The absolute configuration of the norlignan (+)-nyasol was determined to be S by comparison of the experimental vibrational circular dichroism data with first-principle calculations taking into account the eight lowest energy conformations. The established absolute configuration of (+)-nyasol enables establishment of the absolute configuration of (-)-hinokiresinol, which is concluded to be S. A total synthesis and resolution of hinokiresinol has been performed to resolve the conflicting reports of the coupling constant of the vinylic protons of the disubstituted double bond in this molecule. Racemic hinokiresinol was resolved. Both enantiomers possess the same antiplasmodial activity.