874210-29-4

Basic information

• Product Name: 1,3-Benzenedicarboxylic acid, 4,6-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-, dimethyl ester
• CAS NO: 874210-29-4
• Molecular Formula: C24H38O12
• Molecular Weight: 518.559
• Mol File: 874210-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedicarboxylic acid, 4,6-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarboxylic acid, 4,6-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-, dimethyl ester(874210-29-4)
• EPA Substance Registry System: 1,3-Benzenedicarboxylic acid, 4,6-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-, dimethyl ester(874210-29-4)

Safety Data

• Hazardous Substances Data: 874210-29-4(Hazardous Substances Data)

Upstream product

• 52959-28-1 dimethyl 4,6-dihydroxyisophthalate 
• 62921-74-8 2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate 
• 72593-77-2 3,6,9-trioxadecyl bromide 
• 108-46-3 recorcinol 
• 19829-74-4 4,6-dihydroxyisophthalic acid 

Downstream Products

• 1250403-76-9 C₂₂H₃₈N₄O₁₀ 
• 773866-29-8 4,6-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-isophthaloyl dichloride 
• 936354-38-0 4,6-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-N-(2-tritylsulfanyl-ethyl)-isophthalamic acid 
• 936354-31-3 C₆₄H₉₆N₆O₂₆ 
• 936352-81-7 C₅₆H₈₂N₄O₂₄ 
• 936347-09-0 (5-(methoxycarbonylmethylcarbamoyl)-2,4-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}benzoylamino)acetic acid methyl ester 
• 492465-50-6 4,6-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}isophthalic acid 
• 874210-38-5 4,6-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-isophthalic acid monomethyl ester 

Relevant articles and documents

Polyhydrazide-Based Organic Nanotubes as Efficient and Selective Artificial Iodide Channels

Reported herein is a series of pore-containing polymeric nanotubes based on a hydrogen-bonded hydrazide backbone. Nanotubes of suitable lengths, possessing a hollow cavity of about a 6.5 ? diameter, mediate highly efficient transport of diverse types of anions, rather than cations, across lipid membranes. The reported polymer channel, having an average molecular weight of 18.2 kDa and 3.6 nm in helical height, exhibits the highest anion-transport activities for iodide (EC50=0.042 μm or 0.028 mol % relative to lipid), whcih is transported 10 times more efficiently than chlorides (EC50=0.47 μm). Notably, even in cholesterol-rich environment, iodide transport activity remains high with an EC50 of 0.37 μm. Molecular dynamics simulation studies confirm that the channel is highly selective for anions and that such anion selectivity arises from a positive electrostatic potential of the central lumen rendered by the interior-pointing methyl groups.

Synthesis of crescent aromatic oligoamides

This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.