878671-95-5

Basic information

• Product Name: NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-
• Synonyms: NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-;1-Cyclopropyl-4-isothiocyanatonaphthalene;1-CYCLOPROPYL-4-ISOTHIOCYANATO-;lesinurad int.1-Cyclopropyl-4-isothiocyanatonaphthalene;NAPHTHALENE,1-CYCLOPROPYL-4-ISOTHIOCYANATO-1-;1-Cyclopropyl-4-Isothiocyanate Naphthalene;Lesinurad Impurity 17
• CAS NO: 878671-95-5
• Molecular Formula: C₁₄H₁₁NS
• Molecular Weight: 225.31
• EINECS: 639-683-0
• Mol File: 878671-95-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 394.6±21.0 °C(Predicted)
• Appearance: /
• Density: 1.21
• CAS DataBase Reference: NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-(878671-95-5)
• EPA Substance Registry System: NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-(878671-95-5)

Safety Data

• Hazardous Substances Data: 878671-95-5(Hazardous Substances Data)

Usage

General Description

1-Cyclopropyl-4-isothiocyanatonaphthalene is a chemical compound that belongs to the organic group known as naphthalenes, characterized by a naphthalene moiety. The naphthalene moiety is a polycyclic aromatic hydrocarbon made up of two fused benzene rings. The term 'isothiocyanate' signifies the presence of a functional group containing a sulfur, carbon, and nitrogen atom, with the nitrogen bound to the carbon and the sulfur. The 'Cyclopropyl' element indicates a three-membered ring structure within the molecule. The properties and potential applications of this molecule are largely dependent on its structure and functional groups, and it can potentially be utilized in organic synthesis and pharmaceutical chemistry.

Upstream product

• 25033-19-6 1-cyclopropyl-naphthalene 

Downstream Products

• 878671-98-8 2-((5-amino-4-(4-cyclopropyl-naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid methyl ester 
• 878672-00-5 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid 
• 1533519-86-6 N-(4-cyclopropylnaphthalen-1-yl)-2-formylhydrazine-1-thiocarboxamide 
• 1533519-85-5 2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-yl)thio)acetic acid methyl ester 
• 1533519-84-4 4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol 
• 878672-00-5 (-)-2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid 
• 878672-00-5 (+)-2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid 

Relevant articles and documents

Naphthyl thiocarbonyl compound as well as preparation method and application thereof

The invention provides a naphthyl thiocarbonyl compound of a structural formula I. The invention further provides a preparation method of the compound and application of the compound in preparation ofa lesinurad key intermediate 1-cyclopropylnaphthalene-4-benzyl isothiocyanate of a structural formula VII. The structural formula is as shown in the specification. In the formula, R represents hydroxyl or thio.

Optically pure thioacetic compound

The invention belongs to the field of pharmacy and relates to an optically pure thioacetic compound and application thereof to medicine. The optically pure thioacetic compound comprises levorotatory 2-(5-bromo-4-(4-cyclopropyl-naphthalene-1-base)-4H-1,2,4-triazole-3-based sulfenyl) acetic acid and dextral 2-(5-bromo-4-(4-cyclopropyl-naphthalene-1-base)-4H-1,2,4-triazole-3-based sulfenyl) acetic acid.

POLYMORPHIC, CRYSTALLINE AND MESOPHASE FORMS OF SODIUM 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETATE, AND USES THEREOF

Crystalline polymorphs and solid mesophase forms of sodium 2-(5-bromo-4- (4-cyclopropylnaphthalen-l-yl)-4H-l,2,4-triazol-3-ylthio)acetate are described. In addition, pharmaceutical compositions and uses of such compositions for the treatment of a variety of diseases and conditions are provided.