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878671-98-8

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  • High purity Methyl 2-[[5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetate CAS No.:878671-98-8

    Cas No: 878671-98-8

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  • methyl 2-(5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate

    Cas No: 878671-98-8

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878671-98-8 Usage

General Description

The chemical "Acetic acid, 2-[[5-amino-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, methyl ester" is a compound that consists of acetic acid, a 1,2,4-triazole ring, and a thiol group. It also contains a cyclopropyl group and a naphthalenyl group. The compound is in the form of a methyl ester, meaning it contains a methyl group bonded to the carboxyl group of the acetic acid. This chemical is used in various applications in the pharmaceutical and agricultural industries, particularly as an antifungal agent. It has potential therapeutic uses and is also used as a research reagent in biochemical and biomedical studies.

Check Digit Verification of cas no

The CAS Registry Mumber 878671-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,6,7 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 878671-98:
(8*8)+(7*7)+(6*8)+(5*6)+(4*7)+(3*1)+(2*9)+(1*8)=248
248 % 10 = 8
So 878671-98-8 is a valid CAS Registry Number.

878671-98-8Relevant articles and documents

Triazole-naphthalene based fluorescent chemosensor for highly selective naked eye detection of carbonate ion and real sample analyses

Ayyanar, Siva,Chinnadurai, Chithiraikumar,Chinnamadhaiyan, Muniyappan,Muniyasamy, Harikrishnan,Nelson, Malini

, (2021)

Herein, the design and synthesis of triazole-naphthalene hybrid for selective colorimetric and fluorometric sensing of carbonate ion has been reported. The probe has been thoroughly characterized by 1H and 13C NMR and HRMS spectroscopy. CK exhibits an excellent selectivity and sensitivity towards carbonate ions over other anions by changes in both UV–Vis absorption spectra and emission spectra. The limit of detection of carbonate ion in absorbance and emission spectra has 7.2 nM and 1.8 μM respectively. The plausible sensing was confirmed with the help of the Job's plot, FTIR, NMR titration and theoretical studies. Also, naked eye detection method of carbonate from colorless to yellow color is the most conspicuous application of probe CK. The receptor CK providing valuable practical sensor for environmental analyses of carbonate ion. Further, we mimic new logic gate circuit by using the sensing performance of carbonate ion with probe.

Preparing method of triazole thioglycolic acid compound for curing metabolic arthritis

-

, (2016/10/09)

The invention discloses a preparing method of a triazole thioglycolic acid compound for curing metabolic arthritis. According to the method, compound II and compound III are utilized as initial materials and are generated into intermediate compound IV through Suzuki reaction; then nucleophilic substitution happens between the intermediate compound IV and 1,1minute-thiocarbonyl polypyridobisinudazole to generate intermediate compound V; the compound V generates intermediate compound VI through cyclization reaction, and then nucleophilic substitution happens between the compound VI and methyl chloroacetate to generate intermediate compound VII; the intermediate compound VII generates intermediate compound VIII through bromination reaction; and a target product 2-((5-bromine-4-(4-cyclopropyl naphthalene-1-yl)-4H-1,2,4-triazole-3-yl)sulfenyl) acetic acid (I) is generated through hydrolysis reaction. The preparing method is high in selectivity and simple to operate and avoids poisonous reagents and rigorous reacting conditions. Compared with an original synthetic method, the reacting time of the preparing method is shortened, the energy consumption is reduced, and the reaction yield is improved.

POLYMORPHIC, CRYSTALLINE AND MESOPHASE FORMS OF SODIUM 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETATE, AND USES THEREOF

-

, (2011/08/03)

Crystalline polymorphs and solid mesophase forms of sodium 2-(5-bromo-4- (4-cyclopropylnaphthalen-l-yl)-4H-l,2,4-triazol-3-ylthio)acetate are described. In addition, pharmaceutical compositions and uses of such compositions for the treatment of a variety of diseases and conditions are provided.

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