878674-71-6

Basic information

• Product Name: 2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fluoro-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester
• Synonyms: 2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fluoro-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester
• CAS NO: 878674-71-6
• Molecular Weight: 608.623
• Mol File: 878674-71-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fluoro-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fluoro-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester(878674-71-6)
• EPA Substance Registry System: 2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fluoro-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester(878674-71-6)

Safety Data

• Hazardous Substances Data: 878674-71-6(Hazardous Substances Data)

Upstream product

• 136705-25-4 (4-hydroxy-phenyl)-succinic acid dimethyl ester 
• 878674-22-7 2-[5'-fluoro-5-formyl-2'-methoxy-6-(2-methoxy-ethoxymethoxy)-biphenyl-3-yl]-succinic acid dimethyl ester 
• 878673-54-2 2-[3-bromo-5-formyl-4-(2-methoxy-ethoxymethoxy)-phenyl]-succinic acid dimethyl ester 
• 68827-43-0 4-amidino-1,2-phenylenediamine 

Relevant articles and documents

Factor VIIa inhibitors: Improved pharmacokinetic parameters

Efforts to improve the potency and pharmacokinetic properties of small molecule factor VIIa inhibitors are described. Small structural modifications to existing leads allow the modulation of half-life and clearance, potentially making these compounds suitable candidates for drug development.