879-15-2

Basic information

• Product Name: 1(2H)-Naphthalenone,2-diazo-
• CAS NO: 879-15-2
• Molecular Weight: 170.17
• Mol File: 879-15-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1(2H)-Naphthalenone,2-diazo- (CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Naphthalenone,2-diazo- (879-15-2)
• EPA Substance Registry System: 1(2H)-Naphthalenone,2-diazo- (879-15-2)

Safety Data

• Hazardous Substances Data: 879-15-2(Hazardous Substances Data)

Usage

General Description

1(2H)-Naphthalenone,2-diazo- is a chemical compound that belongs to the class of diazo compounds, which are characterized by the presence of a diazo group (-N=N-). It is derived from naphthalenone, a bicyclic aromatic compound, through a diazo coupling reaction. 1(2H)-Naphthalenone,2-diazo- is a yellow to orange crystalline solid that is typically used as a reagent in organic synthesis, specifically in the introduction of the diazo group into other organic compounds. The diazo group is a versatile functional group that can undergo a variety of chemical transformations, making 1(2H)-Naphthalenone,2-diazo- a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Due to its reactivity and potentially hazardous nature, it must be handled with care and used in a controlled manner.

Upstream product

• 4323-69-7 [1]naphthyl-nitro-amine 
• 41772-23-0 1-hydroxy-2-naphthylamine hydrochloride 
• 524-42-5 1,2-naphthoquinone 
• 606-41-7 2-amino-1-naphthol 
• 7732-18-5 water 
• 7758-99-8 copper(II) sulfate 
• 90-15-3 α-naphthol 
• 135-19-3 β-naphthol 
• 68432-16-6 1(2H)-naphthalenone 

Downstream Products

• 571-60-8 1,4-Dihydroxynaphthalene 
• 111061-32-6 2,2'-binaphthyl-1,1',4,4'-tetrol 
• 76939-81-6 1-(benzyloxy)-2-bromonaphthalene 
• 20686-65-1 2-methyloxazolo<4,5-a>naphthalene 
• 39891-79-7 methyl 1H-indene-3-carboxylate 
• 1888-41-1 2-methoxy-1-naphthol 
• 6336-79-4 1,2-naphthalenediol diacetate 
• 574-00-5 1,2-Dihydroxynaphthalene 
• 60433-62-7 2-phenylnaphthalen-1-ol 
• 581-80-6 4,4'-bis(trifluoromethyl)biphenyl 
• 1292303-42-4 C₁₇H₁₁F₃O 
• 1292303-41-3 C₁₇H₁₄O₂ 
• 604-53-5 1,1'-bisnaphthalene 
• 116346-04-4 1,2'-binaphthalene-1'-ol 

Relevant articles and documents

Rh(II)-catalyzed formal [3+3] cycloaddition of diazonaphthoquinones and propargyl alcohols: Synthesis of 2,3-dihydronaphtho-1,4-dioxin derivatives

A Rh(II)-catalyzed formal [3+3] cyclization of diazonaphthoquinones and propargyl alcohol is reported to afford 2,3-dihydro-1,4-benzodioxins. Various terminal propargyl alcohols react with diazonapthoquinone in the presence of Rh2(OAc)4/s

Rh(iii)-Catalyzed straightforward arylation of 8-methyl/formylquinolines using diazo compounds

A straightforward Rh(iii)-catalyzed general strategy was developed for the introduction of naphthol/phenol moieties to the C(sp3)-H bond of 8-methylquinoline using diazonaphthalen-2(1H)-ones/quinone diazides. The developed method was further extended towards the arylation of 8-formylquinolines to accomplish diarylketone derivatives. The method is simple, relatively rapid, and chemo and regioselective with a wide scope and functional group tolerance. The synthetic utility was established through gram-scale synthesis and biologically active molecule construction.

Ir(III)-catalyzed direct C-H functionalization of arylphosphine oxides: A strategy for MOP-type ligands synthesis

Diazo compounds as coupling partners are efficiently applied to Ir(III)-catalyzed direct C-H functionalization of arylphos-phine oxides. Involving C-H activation, carbene insertion, and tautomerism, this reaction proceeds under mild conditions, thus proving an approach to the synthesis of MOP-type ligand precursor in a single step. The utility of this transformation has been further demonstrated in ligand synthesis as well as in the construction of phosphole framework.