879-71-0

Basic information

• Product Name: N-(butan-2-yl)benzamide
• Synonyms: benzamide, N-(1-methylpropyl)-; N-sec-Butylbenzamide
• CAS NO: 879-71-0
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• Mol File: 879-71-0.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 333°C at 760 mmHg
• Flash Point: 196.9°C
• Density: 0.986g/cm³
• Vapor Pressure: 0.000141mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: N-(butan-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(butan-2-yl)benzamide(879-71-0)
• EPA Substance Registry System: N-(butan-2-yl)benzamide(879-71-0)

Safety Data

• Hazardous Substances Data: 879-71-0(Hazardous Substances Data)

Upstream product

• 7007-15-0 3-benzoyl-1,3-oxazolidin-2-one 
• 33966-50-6 SEC-BUTYLAMINE 
• 2902-69-4 2,2,2-trichloroacetophenone 
• 22355-34-6 dicyclohexylammonium benzoate 
• 98-88-4 benzoyl chloride 
• 78-93-3 butanone 
• 54394-74-0 1-Phenyl-2-methyl-1-butanon-anti-oxim 
• 6343-27-7 1-benzoylpyrrolidine-2,5-dione 
• 65-85-0 benzoic acid 
• 27891-03-8 2-Brom-N,N-disek.butyl-benzamid 
• 27891-00-5 2-Chlor-N,N-disek.butyl-benzamid 
• 75058-67-2 2-methyl-1-phenylbutan-1-imine 
• 1575-95-7 N-acetylbenzamide 
• 78-92-2 iso-butanol 

Downstream Products

• 78089-89-1 N-sec-Butyl-thiobenzimidic acid methyl ester; hydriodide 
• 46120-25-6 N-sec-butyl-N-benzylamine 
• 33189-79-6 N-sec-butyl-N-nitroso-benzamide 
• 64528-55-8 N-(1-Methylpropyl)thiobenzamid 

Relevant articles and documents

Photocatalysis in Aqueous Micellar Media Enables Divergent C-H Arylation and N-Dealkylation of Benzamides

Photocatalysis in aqueous micellar media has recently opened wide avenues to activate strong carbon-halide bonds. So far, however, it has mainly explored strongly reducing conditions, restricting the available chemical space to radical or anionic reactivity. Here, we demonstrate a controllable, photocatalytic strategy that channels the reaction of chlorinated benzamides via either a radical or a cationic pathway, enabling a chemodivergent C-H arylation or N-dealkylation. The catalytic system operates under mild conditions with methylene blue as a photocatalyst and blue LEDs as the light source. Factors determining the reactivity of substrates, their selectivity, and preliminary mechanistic studies are presented.

An open-source approach to automation in organic synthesis: The flow chemical formation of benzamides using an inline liquid-liquid extraction system and a homemade 3-axis autosampling/product-collection device

Several open-source hardware and software technologies (RAMPS, Python, PySerial, OpenCV) were used to control an automated flow chemical synthesis system. The system was used to effect the synthesis of a series of benzamides. An inexpensive Raspberry Pi single board computer provided an electronic interface between the control computer and the RAMPS motor driver boards.

TfOH catalyzed One-Pot Schmidt–Ritter reaction for the synthesis of amides through N-acylimides

A One-Pot tandem Schmidt–Ritter process for the synthesis of amides has been developed using the super acid as catalyst. The in situ generated aryl/aliphatic nitriles from the reaction of aldehydes and sodium azide in the presence of TfOH and AcOH (Schmidt reaction) react with suitable alcohol (Ritter reaction) to give the amides. For the first time we observed that during the Schmidt process N-acylimides were generated along with nitriles, interestingly these N-acylimides also participated in the Ritter reaction.