88139-65-5Relevant articles and documents
Total synthesis of thienamycin analogs - III. Synthesis of 2-aryl and 2-heteroaryl analogs of theinamycin
Cama,Wildonger,Guthikonda,et al.
, p. 2531 - 2549 (2007/10/02)
The total syntheses of 2-aryl and 2-heteroaryl carbapen-2-em-3-carboxylic acids with and without a 6-hydroxyethyl side chain, using Wittig cyclization for formation of the bicyclic ring system is described. Antibacterial activity of the compounds synthesized is discussed.