885278-98-8 Usage
Description
ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is a chemical compound with the molecular formula C12H12N2O3, belonging to the indazole derivative class. It is recognized for its diverse biological activities and is a valuable asset in medicinal chemistry and drug discovery due to its potential pharmacological properties.
Used in Medicinal Chemistry:
ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is used as a building block for the synthesis of various biologically active molecules. Its structure and properties make it instrumental in the development of new pharmaceutical drugs, contributing to advancements in healthcare.
Used in Drug Discovery:
In the field of drug discovery, ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE serves as a key component in the creation of novel compounds with therapeutic potential. Its versatility allows researchers to explore its applications in treating a range of diseases and conditions.
Used in Agrochemicals:
ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is also utilized in the agrochemical industry, where it is employed as a precursor for the synthesis of biologically active molecules with applications in agriculture. This includes the development of pesticides, herbicides, and other products that enhance crop protection and yield.
Used in Research and Development:
For researchers and scientists, ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE is a valuable tool in the lab. Its unique properties facilitate the exploration of new chemical pathways and the creation of innovative medications and agricultural products, driving scientific progress and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 885278-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 885278-98:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*8)+(2*9)+(1*8)=238
238 % 10 = 8
So 885278-98-8 is a valid CAS Registry Number.
885278-98-8Relevant articles and documents
High-affinity fluorescent ligands for the 5-HT3 receptor
Simonin, Jonathan,Vernekar, Sanjeev Kumar V.,Thompson, Andrew J.,Hothersall, J. Daniel,Connolly, Christopher N.,Lummis, Sarah C.R.,Lochner, Martin
supporting information; scheme or table, p. 1151 - 1155 (2012/03/26)
The synthesis, photophysical and biological characterization of a small library of fluorescent 5-HT3 receptor ligands is described. Several of these novel granisetron conjugates have high quantum yields and show high affinity for the human 5-HT3AR.
Facile and efficient synthesis of indazole derivatives by 1,3-cycloaddition of arynes with diazo compounds and azomethine imides
Jin, Tienan,Yang, Fan,Yamamoto, Yoshinori
scheme or table, p. 957 - 972 (2010/01/19)
N-Unsubstituted indazoles 3 and 1-arylindazoles 4 are readily available in good to high yields through [3+2] cycloaddition of 2-(trimethylsilyI)aryl triflates 1 and diazo compounds in the presence of KF or CsF under mild reaction conditions. Furthermore, we found that azomethine imides also underwent cycloaddition reaction with 2-(trimethylsilyl)phenyl triflates (la) in the presence of KF to afford indazolone derivatives 6 in moderate yields.
An efficient, facile, and general synthesis of 1H-indazoles by 1,3-dipolar cycloaddition of arynes with diazomethane derivatives
Jin, Tienan,Yamamoto, Yoshinori
, p. 3323 - 3325 (2008/03/12)
(Chemical Equation Presented) Take your pick: Both N-unsubstituted and 1-aryl 1H-indazoles are available in good to high yields through the [3+2] cycloaddition of benzynes derived from o-silylaryl triflates with diazomethane derivatives (see scheme). In the presence of KF/[18]crown-6, the N-unsubstituted 1H-indazole is formed, whereas the 1-arylated product is obtained regioselectively with CsF and an excess of the triflate.