89048-27-1Relevant articles and documents
QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE
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Page/Page column 51, (2014/05/24)
The present invention relates to novel nitric oxide donor compounds for the use in the treatment and/or prophylaxis of hypertensive glaucoma, normotensive glaucoma and ocular hypertension.
NOVEL BENZOQUINONE DERIVATIVES AND USE THEREOF AS MODULATORS OF MITOCHONDRIAL FUNCTION
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Page/Page column 56, (2012/03/10)
The present invention relates to novel benzoquinone derivatives. The compounds are efficient as modulators of mitochondrial function and as such are useful for the treatment of pathological conditions where mitochondrial function is impaired.
Benzoquinone derivatives and production thereof
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, (2008/06/13)
A novel benzoquinone derivative of the general formula: STR1 [wherein R1 and R2 are the same or different and each is methyl or methoxy; n is an integer of 0 to 21; m is 0 or 1, Z is a group of the formula: STR2 (wherein R3 and R4 are the same or different and each is hydrogen or an alkyl group which may optionally be substituted or, R3 and R4 together with the adjacent nitrogen atom form a morpholino group), a group of the formula: --COR5 (wherein R5 is an α-amino acid residue or a substituted or unsubstituted glucosamine residue), a group of the formula: STR3 (wherein R6 is a divalent hydrocarbon group of 1 to 3 carbon atoms), a group of the formula: STR4 (wherein R6 has the same meaning as defined above) or a group of the formula: --CH=CHl --COR7 (wherein l is an integer of 1 to 4 and R7 is hydroxy, methoxy or methyl)] has protocollagen-proline hydroxylase inhibiting activity, collagen biosynthesis inhibiting activity and 5-lipoxygenase suppressant activity, and is useful for the prevention and treatment of such diseases as pulmonary fibrosis, hepatocirrhosis, nephrosclerosis, arteriosclerosis, scleroderma, myelofibrosis and chronic arthritis or for the prevention and treatment of asthma, allergic rhinitis, urticaria, etc.