89691-67-8

Basic information

• Product Name: 1-(2-BroMo-4-Methoxy-phenyl)-ethanone
• Synonyms: 2-Bromo-4-methoxyacetophenone
• CAS NO: 89691-67-8
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07056
• Mol File: 89691-67-8.mol
• Article Data: 28

Chemical Properties

• Melting Point: 69–71°C
• Boiling Point: 309.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.421±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(2-BroMo-4-Methoxy-phenyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-BroMo-4-Methoxy-phenyl)-ethanone(89691-67-8)
• EPA Substance Registry System: 1-(2-BroMo-4-Methoxy-phenyl)-ethanone(89691-67-8)

Safety Data

• Hazardous Substances Data: 89691-67-8(Hazardous Substances Data)

Usage

Preparation

Obtained by reaction of acetyl chloride with 3-bromoanisole in the presence of aluminium chloride.

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 89691-60-1 1-(2-bromo-4-methoxyphenyl)ethan-1-ol 
• 43192-31-0 2-bromo-4-methoxybenzaldehyde 
• 67-56-1 methanol 
• 1006-39-9 1-(2-bromo-4-fluorophenyl)ethanone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 852946-96-4 2-bromo-1-ethyl-4-methoxybenzene 
• 855239-80-4 N-(2-acetyl-5-methoxyphenyl)benzamide 
• 42465-53-2 1-(2-amino-4-methoxyphenyl)ethanone 
• 3219-34-9 2-(N-Formyl-amido)-4-methoxy-acetophenon 
• 190516-85-9 7-methoxy-4(1H)-oxoquinoline 
• 1196517-15-3 1-(2-cyclohexyl-4-methoxyphenyl)ethan-1-one 
• 91444-13-2 5-methoxy-2-(3-methoxyphenyl)-1H-indole 
• 1389321-66-7 C₁₅H₁₈BrNO₂ 
• 1389321-57-6 C₁₆H₂₀BrNO₂ 
• 21286-57-7 (-)-9-epi-metazocine 
• 1183778-97-3 2-bromo-1-(2-bromo-4-methoxyphenyl)ethan-1-one 
• 1379317-71-1 2-(2-bromo-4-methoxyphenyl)acetaldehyde 

Relevant articles and documents

Derivatizing Tribenzothiophene-Fused Hexa-peri-hexabenzocoronenes with Tunable Optoelectronic Properties

A series of trisbenzothieno[1,2:7,8:13,14]hexa-peri-hexabenzocoronenes were synthesized and characterized by a combination of NMR, 2D NMR, MALDI-TOF MS, UV/Vis absorption spectroscopy, and 2D-WAXS measurement. By structural modulation like decoration of e

The intramolecular reaction of acetophenoneN-tosylhydrazone and vinyl: Br?nsted acid-promoted cationic cyclization toward polysubstituted indenes

In the presence of TsNHNH2, a Br?nsted acid-promoted intramolecular cyclization ofo-(1-arylvinyl) acetophenone derivatives was developed, leading to polysubstituted indenes with complexity and diversity in moderate to excellent yields. In sharp contrast with either the radical or carbene involved cyclization of aldehydicN-tosylhydrazone with vinyl, a cationic cyclization pathway was involved, whereN-tosylhydrazone served as an electrophile and alkylation reagent during this transformation.

Divergent Access to Benzocycles through Copper-Catalyzed Borylative Cyclizations

A copper-catalyzed chemodivergent approach to five- and six-membered benzocycles from dienyl arenes tethered with a ketone has been developed. Through proper choice of coordinating ligands and catalytic conditions, copper-catalyzed borylative cyclization of a single dienyl arene can be diverted to two different pathways, leading to indanols and dihydronaphthalenols with high stereoselectivity. The chiral bidentate bisphosphine ligand (S,S)-Ph-BPE was optimal for asymmetric copper-allyl addition to a tethered ketone via a boat-like transition state, whereas NHC ligands led to boro-allyl addition producing indanols with high diastereoselectivity. (Figure presented.).