89763-93-9

Basic information

• Product Name: 2-FLUORO-4-(TRIFLUOROMETHYL)BENZALDEHYDE
• Synonyms: 2-FLUORO-4-(TRIFLUOROMETHYL)BENZALDEHYDE;ALPHA,ALPHA,ALPHA,2-TETRAFLUORO-P-TOLUALDEHYDE;à,à,à,2-tetrafluoro-p-tolualdehyde;2-Fluoro-4-(trifluoromethyl)benzaldehyde 97%;2-Fluoro-4-(trifluoromethyl)benzaldehyde97%;3-Fluoro-4-formylbenzotrifluoride, alpha,alpha,alpha,2-Tetrafluoro-p-tolualdehyde
• CAS NO: 89763-93-9
• Molecular Formula: C₈H₄F₄O
• Molecular Weight: 192.11
• EINECS: 1312995-182-4
• Product Categories: Benzene series;Benzaldehyde;Aldehydes;C8;Carbonyl Compounds
• Mol File: 89763-93-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 118-119 °C(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless/Liquid
• Density: 1.41 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.36E-07mmHg at 25°C
• Refractive Index: n20/D 1.45(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• BRN: 7703632
• CAS DataBase Reference: 2-FLUORO-4-(TRIFLUOROMETHYL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-4-(TRIFLUOROMETHYL)BENZALDEHYDE(89763-93-9)
• EPA Substance Registry System: 2-FLUORO-4-(TRIFLUOROMETHYL)BENZALDEHYDE(89763-93-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 89763-93-9(Hazardous Substances Data)

Usage

Chemical Properties

colorless to light yellow liquid

Uses

2-Fluoro-4-(trifluoromethyl)benzaldehyde may be used in the synthesis of methyl 3-amino-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylate.

InChI:InChI=1/C20H17F17O6/c1-3-41-9(38)7-12(10(39)42-4-2)5-8(43-11(12)40)6-13(21,22)14(23,24)15(25,26)16(27,28)17(29,30)18(31,32)19(33,34)20(35,36)37/h8H,3-7H2,1-2H3

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 197239-49-9 2-fluoro-4-(trifluoromethyl)benzyl alcohol 

Downstream Products

• 1026956-43-3 (E)-3-(2-Fluoro-4-trifluoromethyl-phenyl)-acrylic acid ethyl ester 
• 183801-25-4 (E)-3-(2-fluoro-4-trifluoromethylphenyl)-propenal 
• 1026683-97-5 (E)-3-(2-Fluoro-4-trifluoromethyl-phenyl)-prop-2-en-1-ol 
• 262608-88-8 3-(2-fluoro-4-trifluoromethyl-phenyl)-acrylic acid 
• 132927-09-4 2-methoxy-4-(trifluoromethyl)benzaldehyde 
• 204707-33-5 α-(2-fluoro-4-trifluoromethylphenyl)-N-t-butylnitrone 
• 1486473-74-8 2-(5-(trifluoromethyl)-2-vinylphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 719277-18-6 N-butyl-N-[2-fluoro-4-(trifluoromethyl)benzyl]amine 

Relevant articles and documents

Elemental fluorine. Part 21. (1) direct fluorination of benzaldehyde derivatives

Direct fluorination of a range of benzaldehyde derivatives gives mixtures of fluorobenzaldehyde and benzoyl fluoride products in ratios that depend upon the nature of the ring substituent Electron-withdrawing substituents give predominantly benzoyl fluoride derivatives, whereas electron-donating substituents lead to fluoroarene systems. Separation of ring-fluorinated products can be easily accomplished by esterification of the benzoyl fluoride side products. Scale-up of these processes to provide significant quantities of appropriate fluorobenzaldehyde systems has also been achieved using continuous flow techniques.