9001-67-6 Usage
Uses
Used in Research and Development:
ACETYLNEURAMINYL HYDROLASE is used as a research tool for studying the binding of human T lymphocytes in sheep pretreated with neuraminidase. It helps in understanding the interaction between the enzyme and immune cells, which can be useful in developing therapeutic strategies for various diseases.
Used in Cancer Research:
The enzyme is used in cancer research to investigate the effect of bile salts on the action of hydrolysis by neuraminidase. This can provide insights into the role of neuraminidase in tumor biology and its potential as a therapeutic target for cancer treatment.
Used in Glycoprotein Characterization:
ACETYLNEURAMINYL HYDROLASE is used as a deglycosylation enzyme to cleave sialic acid residues from glycoproteins, allowing for further characterization using techniques such as SDS-PAGE and MALDI-TOF MS. This helps in the purification, structural analysis, and sequencing of glycoproteins, as well as in removing heterogeneity and charge from them.
Used in Pharmaceutical Industry:
Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method, which can be useful in the development of pharmaceutical products. The enzyme has also been used in a study to investigate the modification of leukemia L1210 tumor cells, indicating its potential use in the development of cancer therapies.
Biochem/physiol Actions
Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells.
Check Digit Verification of cas no
The CAS Registry Mumber 9001-67-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 9001-67:
(6*9)+(5*0)+(4*0)+(3*1)+(2*6)+(1*7)=76
76 % 10 = 6
So 9001-67-6 is a valid CAS Registry Number.