90347-86-7

Basic information

• Product Name: Benzamide, 4-ethynyl- (9CI)
• Synonyms: Benzamide, 4-ethynyl- (9CI);4-Ethynylbenzamide
• CAS NO: 90347-86-7
• Molecular Formula: C₉H₇NO
• Molecular Weight: 145.15798
• Product Categories: AMIDE
• Mol File: 90347-86-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzamide, 4-ethynyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-ethynyl- (9CI)(90347-86-7)
• EPA Substance Registry System: Benzamide, 4-ethynyl- (9CI)(90347-86-7)

Safety Data

• Hazardous Substances Data: 90347-86-7(Hazardous Substances Data)

Usage

General Description

Benzamide, 4-ethynyl- (9CI) is a chemical compound with the molecular formula C9H7NO. It is commonly used in organic synthesis as a precursor for the preparation of various pharmaceuticals and agrochemicals. The 4-ethynyl substitution on the benzamide ring adds unique reactivity and properties to the compound, making it useful in a variety of applications. Benzamide, 4-ethynyl- (9CI) is also known for its potential use as a building block in the development of novel materials and as a starting material in the synthesis of complex organic molecules. Its versatility and reactivity make it a valuable tool in the field of organic chemistry.

Upstream product

• 10602-00-3 4-Ethynyl-benzoic acid 
• 698-67-9 p-bromobenzamide 
• 586-89-0 4-acetyl-benzoic acid 
• 3032-92-6 4-cyanophenylacetylene 
• 863640-43-1 4-(trimethylsilanylethynyl)benzamide 

Downstream Products

• 1357457-35-2 C₁₉H₂₀ClN₅O₄ 
• 1260025-39-5 C₂₄H₁₅ClFN₃O 
• 1108612-40-3 5-(4-Carbamoyl-phenylethynyl)-N-[2-cyano-1-(1H-indol-3-ylmethyl)-ethyl]-2-isopropoxy-benzamide 
• 97923-13-2 1-Diphenylhydroxymethyl-4-(3',3'-diphenylhydroxy-1'-propinyl)-benzol 
• 105791-35-3 1-Diphenylchlormethyl-4-(3'-chlor-3',3'-diphenyl-1'-propinyl)-benzol 
• 97692-08-5 1-Benzhydryliden-4-(3',3'-diphenylpropadienyliden)-1,4-dihydro-benzol 
• 851227-28-6 {4-[3-(4-carbamoylphenylethynyl)-5-isopropyl-4-methoxymethoxybenzyl]-3,5-dimethylphenoxy}acetic acid methyl ester 

Relevant articles and documents

Visible light-mediated synthesis of amides from carboxylic acids and amine-boranes

Here, a photocatalytic deoxygenative amidation protocol using readily available amine-boranes and carboxylic acids is described. This approach features mild conditions, moderate-to-good yields, easy scale-up, and up to 62 examples of functionalized amides with diverse substituents. The synthetic robustness of this method was also demonstrated by its application in the late-stage functionalization of several pharmaceutical molecules.

Rh-Catalyzed Anti-Markovnikov Hydrocyanation of Terminal Alkynes

We report the first highly stereo- and regioselective hydrocyanation of terminal alkynes to furnish E-configured alkenyl nitriles. Acrylonitriles can be accessed on gram scale with broad substrate scope and functional group tolerance. The hydrocyanation reaction employs acetone cyanohydrin as a practical alternative to HCN gas.

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