906371-04-8Relevant articles and documents
Asymmetric synthesis of polyfunctionalized mono-, Bi-, and tricyclic carbon frameworks via organocatalytic domino reactions
Enders, Dieter,Huettl, Matthias R. M.,Raabe, Gerhard,Bats, Jan W.
experimental part, p. 267 - 279 (2009/04/08)
An asymmetric organocatalytic multi-component domino reaction is used as a key process for the stereoselective synthesis of polysubstituted mono- and bicyclic cyclohexene-carbaldehydes. Furthermore, the extension of the domino reaction and further synthetic transformations of the cascade products were investigated. The combination of the three-step cascade with an intramolecular Diels-Alder reaction opens up an entry to tricyclic decahydroacenaphthylene and decahydrophenalene skeletons, which are valuable characteristic carbon cores of natural products.
