90798-46-2

Basic information

• Product Name: 2,3-dibromo-1-phenyl-1-butanone
• Synonyms: 2,3-dibromo-1-phenyl-1-butanone
• CAS NO: 90798-46-2
• Molecular Weight: 305.997
• Mol File: 90798-46-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,3-dibromo-1-phenyl-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-1-phenyl-1-butanone(90798-46-2)
• EPA Substance Registry System: 2,3-dibromo-1-phenyl-1-butanone(90798-46-2)

Safety Data

• Hazardous Substances Data: 90798-46-2(Hazardous Substances Data)

Upstream product

• 495-41-0 1-phenylbut-2-en-1-one 
• 52755-39-2 (2E)-1-phenylbut-2-en-1-ol 
• 100-58-3 phenylmagnesium bromide 
• 495-40-9 propiophenone 
• 877-35-0 2-bromo-1-phenylbutan-1-one 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 71-43-2 benzene 
• 62708-40-1 (E)-1-formyl-2-(2-methylethenyl)benzene 

Downstream Products

• 22965-93-1 (Z)-2-Bromo-1-phenyl-2-butyn-1-one 
• 1533-20-6 1,3-diphenylbutane-1-one 
• 62708-40-1 (E)-1-formyl-2-(2-methylethenyl)benzene 
• 495-41-0 1-phenylbut-2-en-1-one 
• 135524-85-5 [3-Methyl-1,4-bis-(toluene-4-sulfonyl)-piperazin-2-yl]-phenyl-methanone 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 87439-86-9 3-bromo-1-phenylbutan-1-one 
• 87439-87-0 3-Bromo-2-methoxy-1-phenyl-butan-1-one 
• 55830-04-1 2-bromo-1-phenyl-2-buten-1-one 
• 854867-19-9 2,3-dimorpholino-1-phenyl-butan-1-one 
• 873989-37-8 1-phenyl-2,3-dipiperidino-butan-1-one 

Relevant articles and documents

Dibrominated addition and substitution of alkenes catalyzed by Mn2(CO)10

A practical method for the dibromination of alkenes without using molecular bromine is consistently appealing in organic synthesis. Herein, we report Mn-catalyzed dibrominated addition and substitution of alkenes only with N-bromosuccinimide, producing a variety of synthetically valuable dibrominated compounds in moderate to high yields. This journal is

Synthesis of α,β-dibromo ketones by photolysis of α-bromo ketones with N-bromosuccinimide: Photoinduced β-bromination of α-bromo ketones

Irradiation of α-bromopropiophenones in the presence of NBS results in the formation of α,β-dibromopropiophenones, which can be viewed as β-bromination of α-bromopropiophenones. The reaction is believed to go through a series of reactions; photoinduced C–Br bond cleavage, elimination of HBr to give α,β-unsaturated ketone intermediates, and addition of Br2, which are formed by the reaction between HBr and NBS. From mechanistic studies of the reaction, we have also found a very convenient method for α-debromination of the α,β-dibromopropiophenones which is by simple irradiation of the dibromo ketones in acetone or 2-propanol without the use of any additives. Our results demonstrate that bromine can be added into or eliminated from the alpha, beta, or both positions to the carbonyl group by photochemical methods, which make synthetic options of bromine containing carbonyl compounds versatile.

Trifluoromethanesulfonic anhydride-promoted α-bromination of ketones with Grignard reagent or magnesium bromide

The direct α-bromination of various ketones using trifluoromethanesulfonic anhydride and Grignard reagent or magnesium bromide in ether gave the corresponding α-bromo ketones in moderate to good yields under mild reaction conditions.