90904-37-3Relevant articles and documents
Synthesis of 1,4-diketones by Michael addition of O-aroylmandelonitriles involving rearrangement of aroyl group and decyanation
Miyashita,Matsuoka,Numata,Higashino
, p. 448 - 450 (1996)
The anions derived from O-aroylmandelonitriles 1 reacted with Michael addition acceptors such as acrylonitrile (7) and methyl acrylate (10) to give the corresponding 1,4-diketones 12, 13, and 15 in moderate to good yields. Under acidic conditions, the 1,4
A new strategy for the synthesis of α,β-diaroylpropionates promoted by samarium metal in DMF
Liu, Yongjun,Liu, Xi,Zhang, Yongmin
, p. 1667 - 1670 (2007/10/03)
When promoted by samarium in DMF, aroyl chlorides react readily with acrylates to afford α,β-diaroylpropionates in good to excellent yields without pretreating or activating the metallic samarium.
Alkoxycarbonylcarbene Transfer to Acyclic Tertiary Enaminones
Maas,Mueller
, p. 315 - 322 (2007/10/03)
Copper-catalyzed alkoxycarbonylcarbene transfer from methyl or tert-butyl diazoacetate to acyclic enaminoesters 6a,b and enaminocarboxanilide 13 yields vicinal push-pull-substituted cyclopropanes 7a,b, 8, and 14. In contact with dry silica gel, the latter compounds undergo facile ring-opening leading to enaminoesters 9,10, and 15. Treatment with aqueous acid transforms 9 and 10 into 2-acylsuccinates 11 and 12, and 15 into pyrrolinone 16. Methoxycarbonylcarbene transfer to enaminoketones 1a-c does not yield isolable cyclopropanes, but after hydrolytic work-up α-acyl-γ-ketoesters 2a-c are obtained.
