90918-78-8

Basic information

• Product Name: N-methyl-N-(4-nitrophenyl)propionamide
• Synonyms: N-methyl-N-(4-nitrophenyl)propionamide
• CAS NO: 90918-78-8
• Molecular Weight: 208.217
• Mol File: 90918-78-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-methyl-N-(4-nitrophenyl)propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(4-nitrophenyl)propionamide(90918-78-8)
• EPA Substance Registry System: N-methyl-N-(4-nitrophenyl)propionamide(90918-78-8)

Safety Data

• Hazardous Substances Data: 90918-78-8(Hazardous Substances Data)

Upstream product

• 802294-64-0 propionic acid 
• 100-15-2 N-methyl(p-nitroaniline) 
• 4850-93-5 N-(4-nitrophenyl)propionamide 
• 74-88-4 methyl iodide 

Downstream Products

• 1254783-89-5 N-methyI-N-(4-(6-(piperidin-3-ylamino)-9H-purin-2-ylamino)phenyl)propionamide 
• 1254783-88-4 tert-butyl-3-(2-(4-(N-methylpropionamido)phenylamino)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-ylamino)piperidine-1-carboxylate 
• 1254782-72-3 C₂₄H₃₀N₈O₂ 
• 1254783-85-1 N-(4-(6-(1-acryloylpiperidin-3-ylamino)-9H-purin-2-ylamino)phenyl)-N-methylpropionamide 
• 112077-95-9 N-(4-aminophenyl)-N-methylpropionamide 

Relevant articles and documents

Cross-Dehydrogenative Cyclization-Dimerization Cascade Sequence for the Synthesis of Symmetrical 3,3′-Bisoxindoles

The synthesis of symmetrical 3,3′-bisoxindoles from simple acyclic β-oxoanilides is reported. The described method forges three new C-C bonds in a single step via a sequential Mn(OAc)3·2H2O mediated oxidative radical cyclization-fragmentation-dimerization process. The scope of this reaction is demonstrated in the preparation of a variety of 3,3′-bisoxindoles, as well as its application toward the formal synthesis of the Calycanthaceae alkaloid, (±)-folicanthine.

EGFR INHIBITORS AND METHODS OF TREATING DISORDERS

The present invention relates to novel pyrimidine, pyrrolo-pyrimidine, pyrrolo-pyridine, pyridine, purine and triazine compounds which are able to modulate epidermal growth factor receptor (EGFR), including Her-kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.