909274-50-6Relevant articles and documents
Intramolecular Carbonylative C–H Functionalization of 1,2,3- Triazoles for the Synthesis of Triazolo[1,5-a]indolones
Veryser, Cedrick,Steurs, Gert,Van Meervelt, Luc,De Borggraeve, Wim M.
supporting information, p. 1271 - 1276 (2017/04/18)
This study presents a synthesis of 4H-[1,2,3]triazolo[1,5-a]indol-4-ones. The key step in the synthesis of this new heterocyclic scaffold is an intramolecular cyclization via an unprecedented carbonylative C–H functionalization of 1-(2-bromoaryl)-1,2,3-tr
HIV integrase inhibitors
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Page/Page column 37, (2010/11/27)
The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
HIV INTEGRASE INHIBITORS: CYCLIC PYRIMIDINONE COMPOUNDS
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Page/Page column 75-76, (2010/11/27)
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed. Formula: (I).