909277-52-7Relevant articles and documents
Ceramide derivatives and their use as inhibitors of sphingolipid synthesis
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, (2008/06/13)
Ceramide derivatives of the following general formula STR1 are described, wherein the individual radicals have the following meanings: X=--NH or --CH2, R1 =H or C1-11 -alkyl, R2 =C2-9 -alkenyl, wherein the double bond is in α position to the OR3 group R3 =H, C1-6 -alkyl or C1-6 -acyl and R4 =OH, C1-6 -alkoxy or morpholino. These ceramide derivatives represent inhibitors of the biosynthesis of sphingolipids.