91119-04-9

Basic information

• Product Name: 5-(2-phenylethyl)-5-nonanol
• Synonyms: 5-(2-phenylethyl)-5-nonanol
• CAS NO: 91119-04-9
• Molecular Weight: 248.409
• Mol File: 91119-04-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(2-phenylethyl)-5-nonanol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-phenylethyl)-5-nonanol(91119-04-9)
• EPA Substance Registry System: 5-(2-phenylethyl)-5-nonanol(91119-04-9)

Safety Data

• Hazardous Substances Data: 91119-04-9(Hazardous Substances Data)

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 2021-28-5 ethyl dihydrocinnamate 
• 693-04-9 butyl magnesium bromide 
• 109-72-8 n-butyllithium 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 112448-69-8 3-phenyl-1-(1H-pyrrol-1-yl)propan-1-one 
• 173549-40-1 1-(3-phenylpropanoyl)-2,5-dihydropyrrole 
• 542-69-8 1-iodo-butane 
• 501-52-0 3-Phenylpropionic acid 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 101592-82-9 5-(2-cyclohexyl-ethyl)-nonane 
• 101746-51-4 5-phenethyl-nonane 

Relevant articles and documents

A ONE-STEP CONVERSION OF ESTERS TO SECONDARY ALCOHOLS WITH LiBH4-RMgX

A one-pot synthesis of secondary alcohols from esters and LiBH4-RMgX is described.

Tandem addition β-lithiation - Alkylation sequence on α,β-unsaturated aldehydes

A tandem reaction between (E)-cinnamaldehyde, 1a, and phenyllithium affording β-substituted dihydrochalcones was recently reported. NMR spectroscopic studies on the reaction mixture, as well as isotopic exchange reactions and trapping of two intermediates, provide clues on the several mechanistic steps of this new reaction. Extended studies revealed that β-alkyl-substituted α,β-unsaturated aldehydes and aliphatic lithium reagents did not afford good yields of the tandem reaction products, while aromatic lithium reagents gave good results. The aggregation features of the aryllithium reagents and the extended charged delocalization effects are considered to promote β-selectivity. This approach provides a convenient route for the synthesis of a wide variety of β-alkyl-substituted dihydrochalcones.