914223-43-1

Basic information

• Product Name: 3-AMINO-2-FLUOROBENZOIC ACID
• Synonyms: Benzoicacid, 3-aMino-2-fluoro-;3-Carboxy-2-fluoroaniline;3-Amino-2-fluorobenzoicacid98%
• CAS NO: 914223-43-1
• Molecular Formula: C₇H₆FNO₂
• Molecular Weight: 155.13
• EINECS: 1533716-785-6
• Mol File: 914223-43-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 325.9 °C at 760 mmHg
• Flash Point: 150.9 °C
• Appearance: /
• Density: 1.430
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.43±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-2-FLUOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-2-FLUOROBENZOIC ACID(914223-43-1)
• EPA Substance Registry System: 3-AMINO-2-FLUOROBENZOIC ACID(914223-43-1)

Safety Data

• Hazardous Substances Data: 914223-43-1(Hazardous Substances Data)

Usage

General Description

3-AMINO-2-FLUOROBENZOIC ACID is a chemical compound with the molecular formula C7H6FNO2. It is a derivative of benzoic acid with a fluorine atom and an amino group attached to the benzene ring. 3-AMINO-2-FLUOROBENZOIC ACID is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in the development of new drugs and biologically active molecules due to its structural features and functional groups. 3-AMINO-2-FLUOROBENZOIC ACID is also used as a reagent in organic synthesis and chemical research, making it an important intermediate in the production of various compounds.

Upstream product

• 873697-68-8 3-amino-2-fluorobenzonitrile 
• 317-46-4 2-fluoro-3-nitro-benzoic acid 

Downstream Products

• 1244644-50-5 C₃₁H₂₈F₃N₇O₃S₂ 
• 1195768-19-4 3-(2,6-difluorobenzenesulfonamido)-2-fluorobenzoic acid methyl ester 
• 1195768-20-7 N-(3-(2-(2-chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide 
• 1195768-22-9 N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide 
• 873697-71-3 methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate 

Relevant articles and documents

Phenazine-1,6-dicarboxamides: Redox-Responsive Molecular Switches

We introduce phenazine-1,6-dicarboxamides as redox-responsive molecular switches. The reduction of their phenazine core transforms them from hydrogen-bond acceptors into hydrogen-bond donors and thus forces the secondary amide substituents to turn around.

Synthesis and properties of pentafluorosulfanyl group (Sf5)-containing meta-diamide insecticides

Herein, we describe novel pentafluorosulfanyl (SF5) group-containing meta-diamide insecticides. For the facile preparation of the SF5-based compounds 4a–d, practical synthetic methods were applied. Among newly synthesized compounds, 3-benzamido-N-(2,6-dimethyl-4-(pentafluoro-λ6-sulfanyl)phenyl)-2-fluorobenzamide 4d showed (i) a high insecticidal activity, (ii) an excellent selectivity to insects, and (iii) good levels of water solubility and log P values. In this study, we demonstrated that the pentafluorosulfanyl moiety could serve as an attractive functionality for the discovery of a new scope of crop-protecting agents.

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis

A whole organism high-throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei led to the recent discovery of several novel compound classes with low micromolar activity against this organism and without appreciable cytotoxici