921846-29-9Relevant articles and documents
Pyridopyrimidine protein tyrosine phosphatase inhibitors
-
Page/Page column 7; 11-12, (2008/06/13)
The present invention comprises pyridopyrimidinediamine compounds of the general formula I: The compounds of the present invention are potent inhibitors of PTP1B. Accordingly, the invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.