924287-65-0

Basic information

• Product Name: Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate
• Synonyms: Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate
• CAS NO: 924287-65-0
• Molecular Formula: C₉H₅BrFNO₂S
• Molecular Weight: 290.1089032
• Mol File: 924287-65-0.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate(924287-65-0)
• EPA Substance Registry System: Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate(924287-65-0)

Safety Data

• Hazardous Substances Data: 924287-65-0(Hazardous Substances Data)

Usage

General Description

Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate is a chemical compound with the molecular formula C9H5BrFNO2S. It is a derivative of benzo[d]thiazole, which is composed of a benzene ring fused to a thiazole ring. The presence of a bromine and fluorine atom in the compound indicates its potential utility in organic synthesis and pharmaceutical research. The carboxylate group suggests that it may have potential applications in the formation of esters or other organic reactions. Overall, this compound has potential uses in the fields of chemistry and pharmaceutical research due to its unique structure and functional groups.

Upstream product

• 540-80-7 tert.-butylnitrite 
• 924287-64-9 methyl 2-amino-4-fluoro-1,3-benzothiazole-6-carboxylate 
• 403-21-4 3-fluoro-4-nitrobenzoic acid 
• 185629-32-7 methyl 4-amino-3-fluorobenzene carboxylate 
• 185629-31-6 methyl 3-fluoro-4-nitrobenzoate 

Downstream Products

• 1383816-29-2 2-[(1R,3r,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid 
• 1383816-38-3 C₂₉H₂₆F₄N₄O₄S 
• 1383816-28-1 methyl-2-(3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-4-fluorobenzo[d]thiazole-6-carboxylate 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR TREATING LIVER DISORDERS

The present disclosure is directed to FXR agonists, pharmaceutical compositions thereof, and methods of using the same for preventing, treating, or ameliorating fatty liver diseases such as steatosis, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis, either alone or in combination with thyroid receptor agonists.

COMPOUNDS FOR MODULATING FXR

Provided herein are compounds of Formula (I), a stereoisomer, enantiomer or a pharmaceutically acceptable salt thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).

ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF

The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediate