92642-18-7

Basic information

• Product Name: N-(3-acetyl-2-nitrophenyl)acetamide
• Synonyms: acetamide, N-(3-acetyl-2-nitrophenyl)-; N-(3-Acetyl-2-nitrophenyl)acetamide
• CAS NO: 92642-18-7
• Molecular Formula: C₁₀H₁₀N₂O₄
• Molecular Weight: 222.1974
• Mol File: 92642-18-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 459.6°C at 760 mmHg
• Flash Point: 231.8°C
• Density: 1.339g/cm³
• Vapor Pressure: 1.24E-08mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: N-(3-acetyl-2-nitrophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-acetyl-2-nitrophenyl)acetamide(92642-18-7)
• EPA Substance Registry System: N-(3-acetyl-2-nitrophenyl)acetamide(92642-18-7)

Safety Data

• Hazardous Substances Data: 92642-18-7(Hazardous Substances Data)

Upstream product

• 7463-31-2 3-Acetamidoacetophenone 
• 99-03-6 1-(3-aminophenyl)ethanone 
• 108-24-7 acetic anhydride 

Downstream Products

• 89334-34-9 1-(quinoxalin-5-yl)ethanone 
• 1438559-38-6 phenyl(quinoxalin-5-yl)methanone 
• 10203-12-0 3-Amino-β-cyano-α-methyl-2-nitro-styrol 
• 1455-88-5 <3-Azido-2-nitro-phenyl>-aethanon 
• 159724-49-9 monoacetylphenylenediamine 
• 56759-31-0 1-(3-bromo-2-nitrophenyl)ethanone 
• 7137-38-4 1-(3-chloro-2-nitrophenyl)ethan-1-one 
• 92642-20-1 2-nitro-3-(trifluoroacetamido)acetophenone 
• 92642-21-2 3-(methylamino)-2-nitroacetophenone 
• 10203-10-8 3-Acetamino-β-cyano-α-methyl-2-nitro-zimtsaeure 
• 861060-96-0 acetic acid-(3-acetyl-2-amino-anilide) 
• 10202-87-6 1-(3-amino-2-nitrophenyl)ethanone 

Relevant articles and documents

Direct exchange of a ketone methyl or aryl group to another aryl group through ciC bond activation assisted by rhodium chelation

Swapped: Commercially available quinolinone derivatives (1 or 2, see scheme) were reacted with arylboronic acids in the presence of a RhI complex to give aryl(quinolin-8-yl)methanone products 3 in medium to good yields. A mechanism that involves the in situ oxidation of RhI to RhIII by O2 in the presence of CuI was proposed. Copyright

Semisynthetic Enzymes: Characterization of Isomeric Flavopapains with Widely Different Catalytic Efficiencies

Flavopapain 6 has been prepared by alkylation of the active site cysteine-25 of papain with 8α-(bromoacetyl)-10-methylisoalloxazine.This semisynthetic enzyme was shown to serve as a catalyst for the oxidation of dihydronicotinamides, exhibiting saturation kinetics and up to 600-fold rate accelerations relative to a model flavin.This is contrasted to the behavior of flavopapain 9, the product of the modification of papain with 6α-(bromoacetyl)-10-methylisoalloxazine.In this case no catalytic rate enhancement compared to the behavior of a model compound is observed.Since the two isoalloxazines are isomeric, the differences in the activities of the semisynthetic enzymes are interpreted in terms of differences in the geometry of the flavin at the active site.It is also noted that flavopapain 6 can exhibit some chiral discrimination toward optically active dihydronicotinamides.