93-97-0

Basic information

• Product Name: Benzoic anhydride
• Synonyms: Phenyl anhydride;BENZOIC ANHYDRIDE, TECH., 90%;BenzoicAnhydride,~98%;BenzoicAnhydride99%;BENZOIC ANHYDRIDE pure;Banzoyl benzoate;Dibenzoic acid anhydride;Dibenzoic anhydride
• CAS NO: 93-97-0
• Molecular Formula: C14H10O3
• Molecular Weight: 226.23
• EINECS: 202-291-1
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Protecting Agents for Hydroxyl and Amino Groups;Protecting Agents, Phosphorylating Agents & Condensing Agents;Reagents for Oligosaccharide Synthesis;Carboxylic Acid Anhydrides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 93-97-0.mol
• Article Data: 201

Chemical Properties

• Melting Point: 38-42 °C(lit.)
• Boiling Point: 360 °C
• Flash Point: >230 °F
• Appearance: White to almost white/Crystals or Crystalline Powder
• Density: 1.199 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.29E-05mmHg at 25°C
• Refractive Index: nD15 1.57665
• Storage Temp.: Store at RT.
• Solubility: 0.01g/l (experimental)
• Water Solubility: 0.01 g/L
• Sensitive: Moisture Sensitive
• Merck: 14,1092
• BRN: 516726
• CAS DataBase Reference: Benzoic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic anhydride(93-97-0)
• EPA Substance Registry System: Benzoic anhydride(93-97-0)

Safety Data

• Hazard Codes: Xi
• Statements: 37/38-41-36/37/38
• Safety Statements: 26-39-37/39
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• Hazardous Substances Data: 93-97-0(Hazardous Substances Data)

Usage

Chemical Properties

white to almost white crystals or crystalline

Uses

Different sources of media describe the Uses of 93-97-0 differently. You can refer to the following data:
1. Benzoic Anhydride is the more active analogue of benzoic acid formed via dehydration. Benzoic Anhydride is used in the synthesis of a wide range of organic compounds including some dyes. Benzoic Anhyd ride is also used as an arylation agent in the Heck reaction.
2. In organic syntheses, as benzoylating agent in the manufacture of pharmaceuticals, dyes, and intermediates.
3. Benzoic anhydride is used as a benzoylating agent in the manufacture of pharmaceuticals, dyes and intermediates. It serves as an arylation agent in the Heck reaction. It is also used to get benzoic acid through dehydration. Further, it is used to prepare furan-2-yl-phenyl-methanone, which is similar to Friedel-Crafts acylation reaction. In addition to this, it is used for the synthesis of carboxylic esters and lactones.

Preparation

To a flask containing 14.0 gm (0.1 mole) of benzoyl chloride and equipped with a stirrer is added 40 ml of dry dioxane and it is cooled to 5°C.Then 10 ml (0.1 mole) of dry pyridine is rapidly added at 5-10°C followed by 1.0 ml (0.056 mole) of water. After stirring for 10-15 min at 0-5°C, the reaction mixture is then poured into a mixture of 75 ml of cone, hydrochloric acid, 75 gm of cracked ice, and 350 ml of water. The product is filtered, washed first for 1 min with a cold 5% solution of sodium bicarbonate and then with water. The product is dried to afford 11.0 gm (97%), m.p. 43°C (recrystallized from a mixture of ether-petroleum ether).

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 35, p. 1262, 1987 DOI: 10.1248/cpb.35.1262Tetrahedron Letters, 26, p. 1503, 1985 DOI: 10.1016/S0040-4039(00)98536-8

General Description

Benzoic anhydride undergoes Friedel-Crafts acylation reaction with benzene over various ion-exchanged heteropoly acids to yield benzophenone.

Purification Methods

Free it from benzoic acid by washing with NaHCO3, then water, and drying. Crystallise it from *benzene (0.5mL/g) by adding just enough pet ether (b 40-60o) to cause cloudiness, then cool in ice. It can be distilled at 210-220o/20mm. [Beilstein 19 IV 550.]

InChI:InChI=1/C14H10O3/c15-13(11-7-3-1-4-8-11)17-14(16)12-9-5-2-6-10-12/h1-10H

Synthetic route

benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In toluene for 3h; Heating;	99%
With pyridine; 1,1,1-trichloro-3,3,3-trifluoro-propan-2-one; water In toluene for 0.5h; Ambient temperature;	97%
With water; triethylamine In acetone at 20℃; for 1h;	97%

benzoic acid (65-85-0) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20℃; for 0.5h;	99%
With 2,6-dimethylpyridine; tris(2,2'-bipyridyl)ruthenium dichloride; carbon tetrabromide; N,N-dimethyl-formamide at 25 - 30℃; for 12h; Inert atmosphere; Photolysis;	99%
With thionyl chloride In dichloromethane at 22 - 25℃; for 1h;	98.6%

Potassium benzoate (582-25-2) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With N-benzyl-N,N,N-triethylammonium chloride In chloroform at 20℃; for 2h; Acylation;	98%
With 1,4-diaza-bicyclo[2.2.2]octane for 0.1h;	98%

2-benzoyl-4,5-dichloropyridazin-3(2H)-one (155164-66-2) → 4,5-dichloro-2H-pyridazin-3-one (932-22-9) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With zinc(II) chloride In acetonitrile for 7h; Heating;	A n/a B 97%

Potassium benzoate (582-25-2) + benzoic acid (65-85-0) → benzoic acid anhydride (93-97-0)

Conditions	Yield
Stage #1: benzoic acid With trichloroisocyanuric acid; triphenylphosphine In dichloromethane at 0 - 20℃; Stage #2: Potassium benzoate In dichloromethane at 20℃; for 0.833333h; Reagent/catalyst; Solvent; Time;	95%

zinc benzoate (553-72-0) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0)

Conditions	Yield
In toluene at 40℃; for 0.5h;	92%

sodium benzoate (532-32-1) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0)

Conditions	Yield
Pyridine 1-oxide hydrochloride In dichloromethane; water at 22℃; Kinetics; Rate constant; Thermodynamic data; mechanism, effect of agitation, influence of ionic strength, other org. solvents, other temperatures;	A 91.8% B n/a
In dichloromethane; water Thermodynamic data; influence of ionic strength;

benzoyl chloride (98-88-4) + benzoic acid (65-85-0) → benzoic acid anhydride (93-97-0)

Conditions	Yield
cobalt(II) chloride In dichloromethane; acetonitrile at 40℃; various acid chlorides, other carboxylic acids;	91%
cobalt(II) chloride In dichloromethane; acetonitrile at 40℃;	91%
With Fe/SWCNTs at 20℃; for 1.41667h;	90%

benzamide (55-21-0) + benzoic acid (65-85-0) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With aluminum oxide In acetonitrile at 85 - 115℃; for 7h; Concentration; Temperature; Large scale;	91%

methanesulfonyl chloride (124-63-0) + benzoic acid (65-85-0) → Benzoesaeure-methansulfonsaeure-anhydrid (26926-35-2) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With triethylamine In dichloromethane at 0℃;	A 90% B 20%

iodobenzene (591-50-4) + carbon monoxide (201230-82-2) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With 1,3-bis-(diphenylphosphino)propane; water; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 20 - 115℃; under 760.051 Torr; for 6h; Inert atmosphere; Autoclave;	90%

benzyl alcohol (100-51-6) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With tert.-butylhydroperoxide; tetrabutyl phosphonium bromide In water; chlorobenzene at 80℃; for 2.5h; Reagent/catalyst; Solvent; Temperature; Sealed tube;	90%
Multi-step reaction with 2 steps 1: trichloroisocyanuric acid / dichloromethane / 20 °C / Inert atmosphere 2: triethylamine / 1 h / 0 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: trichloroisocyanuric acid / dichloromethane / 20 °C / Inert atmosphere 2: triethylamine; water / dichloromethane / 0 - 20 °C / Inert atmosphere View Scheme

Phenylcarbonyloxy(pyridine-2-thione) (22574-12-5) → 2,2'-dipyridyldisulphide (2127-03-9) + C12H9NO2S (127878-49-3) + S-(pyridin-2-yl) pyridine-2-thiosulfonate (127878-50-6) + benzoic acid anhydride (93-97-0)

Conditions	Yield
In chloroform-d1 at -27℃; for 0.25h; Irradiation;	A 22% B 13% C 20% D 88%
In dichloromethane at 0 - 5℃; for 0.5h; Product distribution; Irradiation; other solvent (CDCl3), temperature (-27 deg C), time (5 min); also other acyl derivatives investigated;	A n/a B 11% C n/a D 84%
In dichloromethane at -27℃; for 0.0833333h; Irradiation;	A n/a B 21% C n/a D 84%

N,N'carbonyldi<2(3H)-benzoxazolethione> (91292-18-1) + benzoic acid (65-85-0) → 3-benzoyl-2(3H)-benzoxazolethione (33388-23-7) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With 1-methyl-pyrrolidin-2-one In pyridine for 2h; Ambient temperature;	A 88% B n/a

disodium terephthalate (10028-70-3) + benzoyl chloride (98-88-4) → C22H14O6 (114833-01-1) + benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0)

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 88% B 1% C 11%
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃;	A 88% B 1% C 11%

sodium maleate (3105-55-3, 5873-57-4, 7704-73-6, 17013-01-3, 18016-19-8, 30915-61-8, 44670-32-8, 54060-75-2, 72383-56-3, 371-47-1) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0)

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 12% B 88%

di(p-anisyl)tellurium dibenzoate (57857-69-9) → di(p-methoxyphenyl)tellurium dichloride (4456-36-4) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With benzoyl chloride In chloroform Heating;	A 87% B 79%

di(p-anisyl)tellurium dibenzoate (57857-69-9) + benzoyl chloride (98-88-4) → di(p-methoxyphenyl)tellurium dichloride (4456-36-4) + benzoic acid anhydride (93-97-0)

Conditions	Yield
In chloroform Heating;	A 87% B 79%

sodium malonate (141-95-7) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0)

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 13% B 87%

1-(benzoyl)piperidine-2,6-dione → benzoic acid anhydride (93-97-0)

Conditions	Yield
With water; scandium tris(trifluoromethanesulfonate) In benzene at 120℃; for 18h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique;	86.9%

2-hydroxy-5-methoxybenzaldehyde (672-13-9) + benzoic acid (65-85-0) → 2-formyl-4-methoxyphenyl benzoate + benzoic acid anhydride (93-97-0)

Conditions	Yield
With iodine; triethylamine; triphenylphosphine In dichloromethane at 0 - 20℃; for 0.333333h;	A 86% B 10%

ethanol (64-17-5) + benzoic acid (65-85-0) → benzoic acid ethyl ester (93-89-0) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With magnesium chloride at 40℃; for 36h;	A 85% B n/a

benzaldehyde (100-52-7) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With tert.-butylhydroperoxide; tetrabutyl phosphonium bromide In chlorobenzene at 80℃; for 3h; Reagent/catalyst; Solvent; Temperature; Sealed tube;	85%
With tert.-butylhydroperoxide In acetonitrile at 80℃; for 2h; Catalytic behavior; Solvent; Reagent/catalyst;	82%
With tert.-butylhydroperoxide; palladium diacetate In chlorobenzene at 140℃; for 2h;	80%

disodium isophthalate (10027-33-5, 18996-36-6, 25458-19-9) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0) + C22H14O6

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 1% B 16% C 83%
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃;	A 1% B 16% C 83%

(C6H5CO2)2Cu → benzoic acid phenyl ester (93-99-2) + o-benzoyloxybenzoic acid (4578-66-9) + benzoic acid anhydride (93-97-0)

Conditions	Yield
In various solvent(s) at 235℃; for 1.33333h;	A 82.1% B 6.3% C 1.5%

C,N-diphenylnitrone (201024-81-9) → benzaldehyde (100-52-7) + benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0) + trans-azobenzene (17082-12-1)

Conditions	Yield
With potassium In tetrahydrofuran for 16h; Product distribution; Mechanism; exclusion of O2, various conditions;	A 42% B 8% C 47% D 82%

2-hydroxy-2-phenylacetophenone (119-53-9) → benzoic acid anhydride (93-97-0)

Conditions	Yield
With diphenyl diselenide; dihydrogen peroxide In acetonitrile at 25℃; for 24h; Reagent/catalyst; Temperature; Solvent; Concentration; Green chemistry;	82%

2-methoxy-phenol (90-05-1) + benzoic acid (65-85-0) → 2-methoxyphenyl benzoate (531-37-3) + benzoic acid anhydride (93-97-0)

Conditions	Yield
With iodine; triethylamine; triphenylphosphine In dichloromethane at 0 - 20℃; for 0.333333h;	A 81% B 14%

benzoic acid (65-85-0) + 1-ethoxyacetylene (927-80-0) → (1-ethoxy)vinyl benzoate (38425-59-1) + benzoic acid anhydride (93-97-0)

Conditions	Yield
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In toluene at 40℃; for 15h;	A 80% B 5%

disodium azelainate (17265-13-3) + benzoyl chloride (98-88-4) → benzoic acid anhydride (93-97-0) + benzoic acid (65-85-0) + C16H20O5 + C23H24O6

Conditions	Yield
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃; Rate constant;	A 3% B 8% C 9% D 80%
With Pyridine 1-oxide hydrochloride In dichloromethane; water at 18℃;	A 3% B 8% C 9% D 80%

methoxybenzene (100-66-3) + benzoic acid anhydride (93-97-0) → 4-Methoxybenzophenone (611-94-9)

Conditions	Yield
With gallium(III) trichloride; silver hexafluoroantimonate In 1,2-dichloro-ethane for 7h; Heating;	100%
With trifluoroacetic acid at 20℃; for 1.5h; Friedel-Crafts Acylation;	98%
With lithium perchlorate In nitromethane at 100℃; for 4h;	97%

(-)-menthol (2216-51-5) + benzoic acid anhydride (93-97-0) → L-menthyl benzoate (612-33-9, 31481-49-9, 38649-18-2, 50465-37-7, 58641-29-5, 71617-14-6, 87038-98-0, 88764-74-3, 88764-75-4, 91840-42-5, 6284-35-1)

Conditions	Yield
With 1-[bis(trifluoromethanesulfonyl)methyl]-2,3,4,5,6-pentafluorobenzene	100%
With 4-(1H,1H-perfluorotetradecyl)-C6F4-CH(SO2CF3)2 In toluene at 70℃; for 14h;	99%
With 4-(dimethylamino)pyridine hydrochloride In toluene at 60℃; for 6h;	98%

isocyanoacetic acid methyl ester (39687-95-1) + benzoic acid anhydride (93-97-0) → methyl 5-phenyl-4-oxazolecarboxylate (38061-18-6)

Conditions	Yield
With P(MeNCH2CH2)3N In tetrahydrofuran 1.) 5 deg C, 15 min, 2.) r.t., 30 min;	100%
With P(MeNCH2CH2)3N for 2h;	90%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran

methyl 4,6-O-benzylidene-3-deoxy-3-iodo-α-D-glucopyranoside (90503-12-1) + benzoic acid anhydride (93-97-0) → methyl 2-O-benzoyl-4,6-O-benzylidene-3-deoxy-3-iodo-α-D-glucopyranoside (127244-71-7)

Conditions	Yield
With dmap; triethylamine In dichloromethane for 2h; Heating;	100%
With triethylamine; dmap In dichloromethane

methyl (3R)-<3-(2)H>-4-O-benzoyl-6-bromo-3,6-dideoxy-α-D-ribo-hexopyranoside (129090-81-9) + benzoic acid anhydride (93-97-0) → methyl (3R)-<3-(2)H>-2,4-di-O-benzoyl-6-bromo-3,6-dideoxy-α-D-ribo-hexopyranoside (131129-47-0)

Conditions	Yield
With dmap; triethylamine In dichloromethane for 2h; Heating;	100%

N2-amino-N3-benzyloxycarbonylaminopyridine (99314-92-8) + benzoic acid anhydride (93-97-0) → (2-Benzoylamino-pyridin-3-yl)-carbamic acid benzyl ester (99314-94-0)

Conditions	Yield
With pyridine Ambient temperature; overnight;	100%

cis-2-(iodomethyl)-3-hydroxytetrahydrofuran (100590-12-3) + benzoic acid anhydride (93-97-0) → cis-2-(iodomethyl)-3-benzoxytetrahydrofuran (109788-30-9, 109788-31-0)

Conditions	Yield
With dmap; triethylamine In tetrahydrofuran Ambient temperature;	100%

benzoic acid anhydride (93-97-0) + C12H12F16O4Te (85878-21-3) → 1,1,2,2-tetrafluoroethyl benzoate (67103-71-3)

Conditions	Yield
at 80 - 120℃;	100%

benzoic acid anhydride (93-97-0) + C12H12F16O4Te (85878-21-3) → 1,1,2,2-tetrafluoroethyl benzoate (67103-71-3) + C20H16F8O6Te (107905-31-7)

Conditions	Yield
at 20℃; for 24h; Yields of byproduct given;	A n/a B 100%

benzoic acid anhydride (93-97-0) + C12H12F16O4Te (85878-21-3) → 1,1,2,2-tetrafluoroethyl benzoate (67103-71-3) + C16H14F12O5Te (107905-28-2)

Conditions	Yield
at 20℃; for 2h; ether as solvent;; Yields of byproduct given;	A n/a B 100%

benzoic acid anhydride (93-97-0) + 17-<(tert-Butyldiphenylsilyl)oxy>-trans-3,4-dihydroxy-15,16-dihydro-11-methylcyclopentaphenanthrene → 17-<(tert-Butyldiphenylsilyl)oxy>-trans-3,4-bis(benzoyloxy)-15,16-dihydro-11-methylcyclopentaphenanthrene

Conditions	Yield
With dmap In dichloromethane for 2h;	100%

(1S,2R,5S)-(+)-menthol (15356-60-2) + benzoic acid anhydride (93-97-0) → (2R,5S)-2-isopropyl-5-methyl-cyclohexyl benzoate (58641-29-5)

Conditions	Yield
erbium(III) triflate In acetonitrile at 50℃; for 1.66667h;	100%
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 20℃; for 92h;	96%
With scandium tris(trifluoromethanesulfonate) In acetonitrile for 20h; Ambient temperature;	95%
With 2,4,6-tris(2,2-bis(trifluoromethylsulfonyl)ethyl)benzene-1,3,5-triol at 70℃; for 3h; Inert atmosphere;	93%

benzoic acid anhydride (93-97-0) + benzyl alcohol (100-51-6) → benzoic acid benzyl ester (120-51-4)

Conditions	Yield
erbium(III) triflate In acetonitrile at 50℃; for 0.833333h;	100%
With bismuth(lll) trifluoromethanesulfonate In acetonitrile for 0.5h; Heating;	98%
With tris(pentafluorophenyl)borate In neat (no solvent) at 20℃; for 0.166667h; Green chemistry;	95%

1,2-dimethoxybenzene (91-16-7) + benzoic acid anhydride (93-97-0) → 3,4-dimethoxybenzophenone (4038-14-6)

Conditions	Yield
With silver perchlorate; niobium pentachloride In nitromethane at 80℃; for 7h; Friedel-Crafts acylation;	100%
With trifluorormethanesulfonic acid; titanium(IV) chloride tris(trifluoromethanesulfonate) In acetonitrile for 12h; Ambient temperature;	94%
Hf[N(SO2C8F17)2]4 In chlorobenzene at 110℃; for 2h;	94%

benzoic acid anhydride (93-97-0) + 2-(trimethylsilyl)ethyl 3-O-benzyl-4,6-O-isopropylidene-β-D-galactopyranoside (191924-37-5) → 2-(trimethylsilyl)ethyl 2-O-benzoyl-3-O-benzyl-4,6-O-isopropylidene-β-D-galactopyranoside

Conditions	Yield
With pyridine for 2h; Ambient temperature;	100%

benzoic acid anhydride (93-97-0) + 2'-deoxy-2'-fluorocytidine (10212-20-1) → N4-benzoyl-2-deoxy-2-fluorocytidine (146954-76-9)

Conditions	Yield
In N,N-dimethyl-formamide at 20℃;	100%
In N,N-dimethyl-formamide at 20℃;	100%
In N,N-dimethyl-formamide	92%

benzoic acid anhydride (93-97-0) + cis-1,4-anhydroerythritol (4358-64-9) → cis-3-benzoyloxy-4-hydroxytetrahydrofuran

Conditions	Yield
ytterbium(III) chloride In tetrahydrofuran Acylation;	100%
With ytterbium(III) chloride In tetrahydrofuran	100%

Upstream product

• 110-86-1 pyridine 
• 60-35-5 acetamide 
• 98-88-4 benzoyl chloride 
• 64-19-7 acetic acid 
• 65-85-0 benzoic acid 
• 280-57-9 1,4-diaza-bicyclo[2.2.2]octane 
• 71-43-2 benzene 
• 94-36-0 dibenzoyl peroxide 
• 56-23-5 tetrachloromethane 
• 506-68-3 bromocyane 
• 532-31-0 silver benzoate 
• 19447-53-1 tetrabenzoyl-hydrazine 
• 532-32-1 sodium benzoate 
• 72021-45-5 benzoyl sulfate 

Downstream Products

• 776-75-0 N-benzoylpiperidine 
• 874-90-8 4-methoxybenzonitrile 
• 2689-59-0 (furan-2-yl)(phenyl)methanone 
• 135-00-2 2-Benzoylthiophene 
• 1585-45-1 N-(diphenylmethylene)benzamide 
• 108129-49-3 N-benzoyloxyurea 
• 321-46-0 2-acetoxy-1-benzoylamino-3,5-dibromo-4-fluoro-benzene 
• 364-25-0 2-acetoxy-3-benzoylamino-1,5-dibromo-4-fluoro-benzene 
• 614-28-8 N-benzoylbenzamide 
• 602-88-0 tribenzamide 
• 65-85-0 benzoic acid 
• 573-34-2 2,4,5-triphenyloxazole 
• 5663-74-1 N-benzoylsalicylamide 
• 67031-71-4 benzoic acid-(2-[2]piperidyl-ethyl ester); hydrochloride 

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Multifunctional amphiphilic hollow carbonaceous spheres assembled into Pickering emulsions exhibit reversible pH-dependent phase-transfer behavior and can efficiently catalyze water/oil biphasic reactions, facilitating the recycling of the catalysts and separation of the products.

Preparation method of symmetric aromatic anhydride compound

The invention discloses a preparation method of a symmetric aromatic anhydride compound, the preparation method comprises the following steps: dissolving alpha-terpilenol and pyridine in a solvent, adding an aroyl chloride solution, and reacting for 8-16 hours to obtain the symmetric aromatic anhydride compound. The alpha-terpilenol and the aroyl chloride are used as raw materials, and the method has the advantages of being easy to operate, mild in reaction condition, high in safety, simple in technological process and post-treatment, low in cost, high in yield of part of products and the like, and is very beneficial to industrialization.

METHOD FOR PRODUCING CARBOXYLIC ACID ANHYDRIDE OR SULFONIC ACID ANHYDRIDE

To provide a method for producing carboxylic acid anhydride or sulfonic acid anhydride in which carboxylic acid anhydride or sulfonic acid anhydride is produced in a simple or easy process using carboxylic acid or sulfonic acid as raw material, and using an industrially available raw material and in an efficient process in industrial practice.SOLUTION: Provided is a method for producing carboxylic acid anhydride or sulfonic acid anhydride, which is a method for producing an acid anhydride by reacting carboxylic acid or sulfonic acid and a halogenating agent, and in which a solvent containing a phosphoric acid ester such as the formula (1) is used. (R1, R2 and R3 are the same or non-identical alkyl group or fluorine-containing alkyl group having 1 to 10 carbon atoms, and at least one is fluorine-containing alkyl group.).SELECTED DRAWING: None