936001-72-8

Basic information

• Product Name: SUCROSE 6'-ACETATE, TECHNICAL GRAD
• Synonyms: SUCROSE 6'-ACETATE, TECHNICAL GRAD;Sucrose-6-acetate;β-D-Fructofuranosyl α-D-Galactopyranoside 6-Acetate
• CAS NO: 936001-72-8
• Molecular Formula: C14H24O12
• Molecular Weight: 384.33316
• Product Categories: Oligosaccharides
• Mol File: 936001-72-8.mol
• Article Data: 26

Chemical Properties

• Melting Point: 69-71°C
• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: SUCROSE 6'-ACETATE, TECHNICAL GRAD(CAS DataBase Reference)
• NIST Chemistry Reference: SUCROSE 6'-ACETATE, TECHNICAL GRAD(936001-72-8)
• EPA Substance Registry System: SUCROSE 6'-ACETATE, TECHNICAL GRAD(936001-72-8)

Safety Data

• Hazardous Substances Data: 936001-72-8(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline Solid

Uses

Sucrose 6’-Acetate, Technical grade 80% (cas# 936001-72-8) is a compound useful in organic synthesis.

Upstream product

• 141-78-6 ethyl acetate 
• 57-50-1 Sucrose 
• 108-05-4 vinyl acetate 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 7732-18-5 water 
• 69257-56-3 D-saccharose 
• 108-24-7 acetic anhydride 
• 1445-45-0 Trimethyl orthoacetate 
• 64-19-7 acetic acid 
• 956499-32-4 1,3(diO-sucrose)dibutyl stannylene 
• 818-08-6 di(n-butyl)tin oxide 
• 631-57-2 Acetyl cyanide 

Relevant articles and documents

Monotin organic compound, preparation method and application thereof

The invention provides a single tin organic compound which is used for synthesizing sucrose-6-carboxylic ester, and the compound is a compound represented by the following formula (1), R , R and R respectively and independently represent straight-chain or branched-chain saturated alkyl groups of C1-C8, straight-chain or branched-chain unsaturated alkyl groups of C2-C8, substituted or unsubstituted saturated cycloalkyl groups of C3-C8, substituted or unsubstituted unsaturated cycloalkyl groups of C3-C8, or aryl groups or substituted aryl groups of C6-C12; and R4 represents a straight chain or branched chain saturated alkyl group of C1 to C6 or an aryl group or a substituted aryl group of C6 to C12. According to the single-tin organic compound, in the process of synthesizing sucrose-6-carboxylic ester, metering and feeding can be accurately carried out, meanwhile, the recovery rate of a catalyst is increased, follow-up chlorination side reactions are reduced, the reaction is fast, energy consumption is small, and the yield in unit volume is higher.

Preparation method of sucrose-6-acetate

The invention relates to a synthesis method of sucrose-6-acetate. The synthesis method comprises the following steps: (1) adding sucrose into an organic solvent DMF (Dimethyl Formamide), heating to 80to 85 DEG C for dissolving, then cooling to 75 DEG C, adding an alkaline solvent and an organic tin compound, and refluxing and reacting with water for 5 to 8 hours, wherein the reflux temperature iscontrolled to be 70 to 75 DEG C; (2) cooling a reactant to -10 DEG C or below, dropwise adding acetic anhydride in the reactant under a stirring condition, and reacting for 3 hours; (3) adding an appropriate amount of water in a reaction solution, extracting the organic tin compound by using a non-polar organic solvent, recycling and reusing after concentrating, and carrying out vacuum distillation on a residual extracted solution for removing the organic solvent, thus obtaining a sucrose-6-acetate solution. A preparation method disclosed by the invention has the following advantages that through the technology disclosed by the invention, the reaction time is reduced, generation of side reaction is reduced, the cost is low, the energy consumption is reduced, and the yield of the sucrose-6-acetate is up to 91 percent.

Synthesis technology of sucralose

The invention discloses a synthesis technology of sucralose. The technology comprises the following steps: reacting a raw material sucrose with acetic anhydride in an organic solvent of an N-amide compound in the presence of an entrainer and a rare earth solid superacid catalyst at 70-95DEG C to generate sucrose-6-acetate, and sequentially carrying out chlorination and alcoholysis reactions on sucrose-6-acetate to generate sucralose. Compared with present sucralose synthesis technologies, the technology has the advantages of simple process, high catalysis activity of the catalyst, small dosage, easy recovery, and low production cost, and is very suitable for industrial production.