942145-04-2 Usage
General Description
3-[(3-Chloro-phenyl)-(2-methanesulfonyloxy-ethoxy)-methyl]-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound with the formula C21H32ClNO5S. 3-[(3-Chloro-phenyl)-(2-methanesulfonyloxy-ethoxy)-methyl]-piperidine-1-carboxylic acid tert-butyl ester is a piperidine carboxylic acid ester and is commonly used in chemical research and pharmaceutical development. It contains a piperidine ring, a chloro-phenyl group, and a methanesulfonyloxy-ethoxy-methyl group, all of which contribute to its potential biological activity. The tert-butyl ester group at the carboxylic acid terminus helps to stabilize the molecule and can also affect its lipophilicity and metabolic stability. 3-[(3-Chloro-phenyl)-(2-methanesulfonyloxy-ethoxy)-methyl]-piperidine-1-carboxylic acid tert-butyl ester may have potential uses in the development of novel drugs or as a research reagent in organic chemistry and biochemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 942145-04-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,1,4 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 942145-04:
(8*9)+(7*4)+(6*2)+(5*1)+(4*4)+(3*5)+(2*0)+(1*4)=152
152 % 10 = 2
So 942145-04-2 is a valid CAS Registry Number.
942145-04-2Relevant articles and documents
Discovery of VTP-27999, an alkyl amine renin inhibitor with potential for clinical utility
Jia, Lanqi,Simpson, Robert D.,Yuan, Jing,Xu, Zhenrong,Zhao, Wei,Cacatian, Salvacion,Tice, Colin M.,Guo, Joan,Ishchenko, Alexey,Singh, Suresh B.,Wu, Zhongren,McKeever, Brian M.,Bukhtiyarov, Yuri,Johnson, Judith A.,Doe, Christopher P.,Harrison, Richard K.,McGeehan, Gerard M.,Dillard, Lawrence W.,Baldwin, John J.,Claremon, David A.
, p. 747 - 751 (2011/12/01)
Structure guided optimization of a series of nonpeptidic alkyl amine renin inhibitors allowed the rational incorporation of additional polar functionality. Replacement of the cyclohexylmethyl group occupying the S1 pocket with a (R)-(tetrahydropyran-3-yl)