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946126-95-0

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946126-95-0 Usage

Uses

2-Fluoro-3-nitrobenzyl Alcohol is used to prepare 2-oxo-2H-benzopyran derivatives as P27 protein inducers to treat diseases accompanying cell proliferation such as cancer, rheumatism and inflammations.

Check Digit Verification of cas no

The CAS Registry Mumber 946126-95-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,1,2 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 946126-95:
(8*9)+(7*4)+(6*6)+(5*1)+(4*2)+(3*6)+(2*9)+(1*5)=190
190 % 10 = 0
So 946126-95-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6FNO3/c8-7-5(4-10)2-1-3-6(7)9(11)12/h1-3,10H,4H2

946126-95-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-Fluoro-3-nitrophenyl)methanol

1.2 Other means of identification

Product number -
Other names 2-FLUORO-3-NITROBENZYLALCOHOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:946126-95-0 SDS

946126-95-0Relevant articles and documents

A3- And A2B-nitrocorroles: Synthesis and antiviral activity evaluation against human cytomegalovirus infection

Bucher, Léo,Bystricky, Kerstin,Desbois, Nicolas,Gallardo, Franck,Gros, Claude P.,Kappler-Gratias, Sandrine

supporting information, p. 771 - 782 (2020/08/03)

Human cytomegalovirus (hCMV) is responsible for several pathologies impacting immunocompromised patients and can trigger life-threatening infection. Several antivirals are available and are used in the clinic, but hCMV resistant strains have appeared and patients have encountered therapeutic failure. Hence, there is a constant need for new best in class or first in class antiviral molecules. We have previously shown that nitrocorroles could be used as a potent anti-hCMV agent without acute toxicity in mice. They therefore represent an excellent platform to perform structure-activity relationship (SAR) studies and to increase efficiency or reduce toxicity. We have generated original A2B- and A3-substituted nitrocorroles and have discovered optimized compounds with selectivity indices above 200. These compounds are easily synthesized in only one to two-step reactions; they are up-scalable and cost efficient. They are therefore excellent candidates for hCMV therapies and they pave the way for a new generation of molecules. This journal is

p27 PROTEIN INDUCER

-

, (2016/10/08)

The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G 1 , G 2 , G 3 and G 8 are each independently selected from -N= etc., Ring G 6 is selected from divalent aryl etc., A is selected from amino etc., G 4 is selected from oxygen etc., G 5 is selected from oxygen etc., G 7 is selected from -CH 2 - etc., and R 2 is selected from C 1-6 alkyl etc.

NOVEL PYRIMIDINE DERIVATIVES 698

-

Page/Page column 171, (2008/12/07)

The invention concerns compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, n, R2, R3, and R4 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4 kinases.

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