95184-61-5

Basic information

• Product Name: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone
• Synonyms: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone;(5-bromothiophen-2-yl)(4-methoxyphenyl)methanone
• CAS NO: 95184-61-5
• Molecular Formula: C₁₂H₉BrO₂S
• Molecular Weight: 297.16766
• Mol File: 95184-61-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 408.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.506±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(95184-61-5)
• EPA Substance Registry System: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(95184-61-5)

Safety Data

• Hazardous Substances Data: 95184-61-5(Hazardous Substances Data)

Usage

General Description

(5-bromo-2-thienyl)(4-methoxyphenyl)Methanone is a chemical compound with the molecular formula C11H9BrO2S. It is an organic compound that belongs to the class of phenyl ketones. (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone is primarily used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It has potential applications in the field of medicinal chemistry, specifically for the development of new drugs with therapeutic properties. The compound's unique structure and functional groups make it an important intermediate in the production of diverse pharmaceutical and agricultural products. Additionally, it may also have potential uses in the field of organic synthesis and material science due to its varied reactivity and properties.

Upstream product

• 4160-63-8 2-(4-methoxybenzoyl)thiophene 
• 151073-94-8 5-bromo-2-thienylzinc bromide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 1003-09-4 2-bromothiophene 

Downstream Products

• 651365-34-3 (5-bromo-[2]thienyl)-(4-hydroxy-phenyl)-ketone 
• 1617505-98-2 (5-(4-(hydroxymethyl)phenyl)thiophen-2-yl)(3-hydroxyphenyl)-methanone 
• 1617506-03-2 (4-hydroxyphenyl)-(5-(3-hydroxyphenyl)sulfanylthiophen-2-yl)methanone 
• 1617506-04-3 (5-(3-hydroxybenzenesulfonyl)-thiophen-2-yl)(4-hydroxyphenyl)methanone 
• 1617506-17-8 (5-(4-(hydroxymethyl)phenyl)thiophen-2-yl)-(3-methoxyphenyl)methanone 
• 1617506-24-7 (4-methoxyphenyl)-(5-(3-methoxyphenyl)sulfanylthiophen-2-yl)methanone 

Relevant articles and documents

Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker

Estradiol is the most potent estrogen in humans. It is known to be involved in the development and proliferation of estrogen dependent diseases such as breast cancer and endometriosis. The last step of its biosynthesis is catalyzed by 17β-hydroxysteroid d

Polymer-supported syntheses of thiophene-containing compounds using a new type of traceless linker

A new type of traceless linker is described for use in polymer-supported (PS) syntheses of thiophene-containing compounds. It is based on the cleavage of PS aryl 2-thienyl ketones by a mixture of potassium t-butoxide and water (typical mol ratio 10:3) in an ethereal solvent. Cleavage occurs to give the soluble thiophene-containing product. The method is used to prepare a range of eight thiophene-containing compounds including a terthiophene and a dialkylquaterthiophene. PS unsymmetrical diaryl ketones incorporating, for example, ortho-methoxyphenyl or pyrrole moieties could also serve as traceless linkers.