96751-61-0

Basic information

• Product Name: 4-Oxazolidinecarboxylicacid,2-oxo-,methylester(9CI)
• Synonyms: 4-Oxazolidinecarboxylicacid,2-oxo-,methylester(9CI);methyl 2-oxooxazolidine-4-carboxylate;RS-2-Oxo-4-oxazolidinecarboxylic acid methyl ester
• CAS NO: 96751-61-0
• Molecular Formula: C₅H₇NO₄
• Molecular Weight: 145.12
• Product Categories: CARBOXYLICESTER
• Mol File: 96751-61-0.mol
• Article Data: 26

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Oxazolidinecarboxylicacid,2-oxo-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxazolidinecarboxylicacid,2-oxo-,methylester(9CI)(96751-61-0)
• EPA Substance Registry System: 4-Oxazolidinecarboxylicacid,2-oxo-,methylester(9CI)(96751-61-0)

Safety Data

• Hazardous Substances Data: 96751-61-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 56-45-1 L-serin 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 75-44-5 phosgene 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 2788-84-3 (S)-serine methyl ester 
• 7693-46-1 4-Nitrophenyl chloroformate 
• 104597-98-0 (S)-2-methoxycarbonyl-1-benzyloxycarbonylaziridine 
• 126496-79-5 (S)-N-tert-butoxycarbonyl aziridine-2-carboxylate methyl ester 
• 120-72-9 indole 
• 74124-79-1 di(succinimido) carbonate 
• 584-08-7 potassium carbonate 
• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 19525-95-2 (S)-2-oxo-oxazolidine-4-carboxylic acid 

Downstream Products

• 264621-76-3 methyl (4S)-3-but-3-enyl-2-oxooxazolidine-4-carboxylate 
• 264621-78-5 but-3-enyl (4S)-3-but-3-enyl-2-oxooxazolidine-4-carboxylate 
• 928112-68-9 methyl (4S)-3-[(4-methoxyphenyl)methyl]-2-oxo-1,3-oxazolidine-4-carboxylate 
• 144542-44-9 (4S)-4-(hydroxymethyl)-1,3-oxazolidin-2-one 
• 173604-32-5 (S)-4-(hydroxydiphenylmethyl)oxazolidin-2-one 
• 132682-23-6 (4R)-4-(hydroxymethyl)-1,3-oxazolidin-2-one 

Relevant articles and documents

Metal-Free Selective Modification of Secondary Amides: Application in Late-Stage Diversification of Peptides

Here we solve a long-standing challenge of the site-selective modification of secondary amides and present a simple two-step, metal-free approach to selectively modify a particular secondary amide in molecules containing multiple primary and secondary amides. Density functional theory (DFT) provides insight into the activation of C-N bonds. This study encompasses distinct chemical advances for late-stage modification of peptides thus harnessing the amides for the incorporation of various functional groups into natural and synthetic molecules.

NOVEL BENZODIOXANE-PIPERIDINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS FOR TREATING NEUROPSYCHIATRIC DISORDERS

The present invention concerns benzodioxane-piperidine with general formula I: wherein notably: R1 represents one or more identical or different substituent(s) on the benzene ring, each independently representing a hydrogen or halogen atom, or a C1-4 alkyl group, or a C1-4 alkoxy group or a C1-4 hydroxyalkyl group or a C1-4 alkylcarbonyl or an alkoxycarbonyl group or an OH group or an SO2R group with R alkyl, or a CN group, or a CF3 group, or an OCF 3 group; n=1, 2 or 3;m=0 or 1, andR2 represents one or more identical or different substituent(s) on the oxazolidinone or morpholinone ring, each independently representing: a hydrogen atom, a C1-4 alkyl group, or a C1-4 alkoxy group, or a C1-4 hydroxyalkyl group, or an alkylcarbonyl group, or an alkoxycarbonyl group, or an alkoxyphenyl group.

A ferrocenyl-DHIPOH/Cu(OAc)2 complex for diastereo- and enantioselective catalysis of the 1,4-addition of glycine derivatives to alkylidene malonates

A planar chiral ferrocene derivative Fc-DHIPOH served as an excellent N,O- chiral ligand for asymmetric copper catalyzed 1,4-addition of glycine derivatives to alkylidene malonates. The corresponding 1,4-adducts were obtained in high yields with excellent enantioselectivities up to 95% ee.