98406-04-3

Basic information

• Product Name: 3-Chloro-5-hydroxybenzoic acid methyl ester
• Synonyms: 3-Chloro-5-hydroxybenzoic acid methyl ester;Methyl 3-chloro-5-hydroxybenzoate
• CAS NO: 98406-04-3
• Molecular Formula: C₈H₇ClO₃
• Molecular Weight: 186.59238
• Mol File: 98406-04-3.mol
• Article Data: 12

Chemical Properties

• Melting Point: 133-135℃
• Boiling Point: 322℃
• Flash Point: 149℃
• Appearance: /
• Density: 1.354
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-Chloro-5-hydroxybenzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-5-hydroxybenzoic acid methyl ester(98406-04-3)
• EPA Substance Registry System: 3-Chloro-5-hydroxybenzoic acid methyl ester(98406-04-3)

Safety Data

• Hazardous Substances Data: 98406-04-3(Hazardous Substances Data)

Usage

General Description

3-Chloro-5-hydroxybenzoic acid methyl ester is a chemical compound with the molecular formula C8H7ClO3. It is a methyl ester derivative of 3-chloro-5-hydroxybenzoic acid, which is commonly used as a starting material in the synthesis of pharmaceuticals and agrochemicals. 3-Chloro-5-hydroxybenzoic acid methyl ester is widely used in organic synthesis as a building block for the preparation of various biologically active compounds. Its unique structure and reactivity make it a valuable tool in medicinal chemistry for the development of new drugs and therapeutic agents. Additionally, this chemical is used in the manufacturing of flavors, fragrances, and dyes, making it a versatile compound with a wide range of applications.

Upstream product

• 82477-67-6 3-chloro-5-methoxy-benzoic acid 
• 51-36-5 3,5-dichlorobenzoic acid 
• 2905-65-9 methyl 3-chlorobenzoate 
• 67-56-1 methanol 
• 53984-36-4 3-chloro-5-hydroxybenzoic acid 
• 408492-29-5 methyl 3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 96826-41-4 methyl 3-chloro-5-methoxybenzoate 

Downstream Products

• 98406-05-4 methyl 3-chloro-5-methoxymethyloxybenzoate 
• 899808-12-9 C₁₄H₂₁ClO₃Si 
• 98406-07-6 3-chloro-5-methoxymethyloxybenzyl chloride 
• 98406-06-5 3-chloro-5-methoxymethyloxybenzyl alcohol 
• 98406-08-7 1-<1-<2-<(3-chloro-5-methoxymethyloxybenzyl)oxy>phenyl>vinyl>-1H-imidazole 
• 98406-10-1 1-<1-<2-<(3-chloro-5-hydroxybenzyl)oxy>phenyl>vinyl>-1H-imidazole hydrochloride 
• 1042023-63-1 C₁₆H₁₅ClO₄ 
• 879542-69-5 3-chloro-5-(2-methoxy-ethoxy)-benzoic acid methyl ester 
• 53985-44-7 3-(benzyloxy)-5-chlorobenzoic acid 
• 899808-15-2 3-chloro-5-hydroxybenzyl acetate 
• 899808-13-0 C₁₃H₂₁ClO₂Si 
• 899808-14-1 C₁₅H₂₃ClO₃Si 

Relevant articles and documents

Sulfoximine-Assisted One-Pot Unsymmetrical Multiple Annulation of Arenes: A Combined Experimental and Computational Study

Discussed herein is an unprecedented Ru-catalyzed one-pot unsymmetrical C-H difunctionalization of arenes comprising intramolecular hydroarylation of olefins and intermolecular annulation of alkynes. This unprecedented 2-fold C-H functionalization is validated on the basis of experimental and density functional theory (DFT) study. The transformation readily occurs with the assistance of methylphenyl sulfoximine (MPS) directing group in the presence of Ru catalyst forming two C-C and one C-N bonds in a single operation. The overall process is atom economical and step-efficient and provides unusual dihydrofuran-fused isoquinolone heterocycles. Further annulation of NH and the proximal o-C-H-arene of isoquinolone with alkynes build highly conjugated novel polycyclic compounds. Overall, three independent annulations in arene motifs are visualized and thoughtfully executed; finally, 5 ring-fused structural entities are constructed forming three C-C and two C-N bonds.

BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

The present invention relates to compounds of the formula (I), wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease ca

BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120

The present invention is directed to benzo-fused heterocyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.