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3-Cyclopentane-D-alanine, also known as (R)-2-Amino-3-cyclopentylpropanoic Acid, is a unique organic compound that plays a significant role in the synthesis of pyridones. These pyridones act as glucokinase activators, which are crucial in the regulation of glucose metabolism. 3-Cyclopentane-D-alanine's distinctive cyclopentane ring and D-alanine moiety contribute to its potential applications in the pharmaceutical industry.

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  • 99295-81-5 Structure
  • Basic information

    1. Product Name: 3-Cyclopentane-D-alanine
    2. Synonyms: (R)-2-amino-3-cyclopentylpropanoic acid;3-CYCLOPENTANE-D-ALANINE;D-beta-Cyclopentylalanine, (R)-alpha-Amino-cyclopentane-propanoic acid;(R)-2-Amino-3-cyclopentylpropionic acid;REF DUPL: D-Cyclopentylalanine;D-3-Cyclopentylalanine;3-Cyclopentyl-D-alanine;(R)-2-aMino-3-cyclopentylpropanoicacidORD-Cyclopentylalanine
    3. CAS NO:99295-81-5
    4. Molecular Formula: C8H15NO2
    5. Molecular Weight: 157.21
    6. EINECS: 145-596-9
    7. Product Categories: Amino Acids;Amino Acid Derivatives;unnatural amino acids
    8. Mol File: 99295-81-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 290.5 °C at 760 mmHg
    3. Flash Point: 129.5 °C
    4. Appearance: /
    5. Density: 1.111 g/cm3
    6. Vapor Pressure: 0.000516mmHg at 25°C
    7. Refractive Index: 1.506
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-Cyclopentane-D-alanine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-Cyclopentane-D-alanine(99295-81-5)
    12. EPA Substance Registry System: 3-Cyclopentane-D-alanine(99295-81-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 99295-81-5(Hazardous Substances Data)

99295-81-5 Usage

Uses

Used in Pharmaceutical Industry:
3-Cyclopentane-D-alanine is used as a key intermediate in the synthesis of pyridones for anti-diabetic therapy. Its involvement in the preparation of glucokinase activators makes it a promising candidate for the development of novel treatments targeting diabetes management.
In the context of anti-diabetic therapy, 3-Cyclopentane-D-alanine is utilized for its ability to contribute to the creation of pyridones that can activate glucokinase, an enzyme pivotal in glucose metabolism. By enhancing glucokinase activity, these pyridones may help improve insulin secretion and glucose tolerance, offering a potential therapeutic approach to managing diabetes and its complications.

Check Digit Verification of cas no

The CAS Registry Mumber 99295-81-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,2,9 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 99295-81:
(7*9)+(6*9)+(5*2)+(4*9)+(3*5)+(2*8)+(1*1)=195
195 % 10 = 5
So 99295-81-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO2/c9-7(8(10)11)5-6-3-1-2-4-6/h6-7H,1-5,9H2,(H,10,11)/t7-/m1/s1

99295-81-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-2-amino-3-cyclopentylpropanoic acid

1.2 Other means of identification

Product number -
Other names D-3-Cyclopentylalanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:99295-81-5 SDS

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