99433-27-9

Basic information

• Product Name: Ethanone, 1-[4-[(4-methylphenyl)thio]phenyl]-
• CAS NO: 99433-27-9
• Molecular Formula: C15H14OS
• Molecular Weight: 242.342
• Mol File: 99433-27-9.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-[(4-methylphenyl)thio]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-[(4-methylphenyl)thio]phenyl]-(99433-27-9)
• EPA Substance Registry System: Ethanone, 1-[4-[(4-methylphenyl)thio]phenyl]-(99433-27-9)

Safety Data

• Hazardous Substances Data: 99433-27-9(Hazardous Substances Data)

Upstream product

• 13329-40-3 4-Iodoacetophenone 
• 106-45-6 para-thiocresol 
• 99-90-1 para-bromoacetophenone 
• 10486-08-5 sodium p-thiocresolate 
• 103-19-5 di(p-tolyl) disulfide 
• 99-91-2 para-chloroacetophenone 
• 624-31-7 4-tolyl iodide 
• 100-19-6 (4-nitrophenyl)ethanone 
• 5720-05-8 4-methylphenylboronic acid 
• 149104-90-5 4-acetylphenylboronic acid 
• 5285-74-5 4-tolyl thiocyanate 
• 403-42-9 1-(4-fluorophenyl)ethanone 

Relevant articles and documents

Bimetallic BaMoO4 nanoparticles for the C-S cross-coupling of thiols with haloarenes

We disclosed new bimetallic BaMoO4 nanoparticles for the C-S cross-coupling reaction. The C-S cross-coupling reaction of alkyl/aryl thiols with haloarenes was accomplished with high yields. The reaction has good functional group tolerance and selectivity. This is an efficient protocol for synthesizing the building blocks of pharmaceuticals containing C-S bonds. The catalyst is recyclable. The unactivated bromo- and 4-acetyl fluoro-arenes can well couple to afford thioethers in high yields. The reaction is believed to proceed by oxidative addition and reductive elimination.

Coupling of thiols and aromatic halides promoted by diboron derived super electron donors

We have proven that pyridine-boryl complexes can be used as superelectron donors to promote the coupling of thiols and aromatic halides through a SRN1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramolecular electron transfer process.

Redox-active benzimidazolium sulfonamides as cationic thiolating reagents for reductive cross-coupling of organic halides

Redox-active benzimidazolium sulfonamides as thiolating reagents have been developed for reductive C-S bond coupling. The IMDN-SO2R reagent provides a bench-stable cationic precursor to generate a portfolio of highly active N-S intermediates, which can be successfully applied in cross-electrophilic coupling with various organic halides. The employment of an electrophilic sulfur source solved the problem of catalyst deactivation and avoided odorous thiols, featuring practical conditions, broad substrate scope, and excellent tolerance.